3D high spectral and spatial resolution imaging ofex vivomouse brain

In-utero 3D High Resolution Fetal Brain Diffusion Tensor Imaging

(a) is one loop of acquired fetal Diffusion transverse data viewed in Transverse, Coronal and Sagittal planes with 2 mm×2 mm in plane resolution, 4mm slice thickness and -2mm gap. (b)-(d) are corresponding reconstructed b0 image, ADC map and FA map respectively with 2 mm×2 mm in plane resolution, and 4mm through slice resolution. (e) is reconstructed anatomical data from a 4-loop of ssTSE dynam...

High Spatial Resolution Lipid Imaging

Robust and High Resolution Hyperpolarized Metabolic Imaging of the Rat Heart at 7 T with 3D Spectral-Spatial EPI

PURPOSE Hyperpolarized metabolic imaging has the potential to revolutionize the diagnosis and management of diseases where metabolism is dysregulated, such as heart disease. We investigated the feasibility of imaging rodent myocardial metabolism at high resolution at 7 T. METHODS We present here a fly-back spectral-spatial radiofrequency pulse that sidestepped maximum gradient strength requir...

High-resolution Confocal Imaging of the Blood-brain Barrier: Imaging, 3D Reconstruction, and Quantification of Transcytosis

The blood-brain barrier (BBB) is a dynamic multicellular interface that regulates the transport of molecules between the circulation and the brain. Transcytosis across the BBB regulates the delivery of hormones, metabolites, and therapeutic antibodies to the brain parenchyma. Here, we present a protocol that combines immunofluorescence of free-floating sections with laser scanning confocal micr...

Spatial and Spectral Resolution Considerations for Imaging Coastal Waters

Current ocean color sensors, for example SeaWiFS and MODIS, are well suited for sampling the open ocean. However, coastal environments are spatially and optically more complex and require more frequent sampling and higher spatial resolution sensors with additional spectral channels. We have conducted experiments with data from Hyperion and airborne hyperspectral imagers to evaluate these needs ...