3D Elemental Imaging with Con-focal X-ray Fluorescence Microscope

3D elemental sensitive imaging using transmission X-ray microscopy.

Determination of the heterogeneous distribution of metals in alloy/battery/catalyst and biological materials is critical to fully characterize and/or evaluate the functionality of the materials. Using synchrotron-based transmission x-ray microscopy (TXM), it is now feasible to perform nanoscale-resolution imaging over a wide X-ray energy range covering the absorption edges of many elements; com...

Contrast with a 3D X-ray Microscope

Quantitative phase imaging with a scanning transmission x-ray microscope.

We obtain quantitative phase reconstructions from differential phase contrast images obtained with a scanning transmission x-ray microscope and 2.5 keV x rays. The theoretical basis of the technique is presented along with measurements and their interpretation.

Elemental and Chemically Specific X-ray Fluorescence Imaging of Biological Systems

Biological Systems M. Jake Pushie,† Ingrid J. Pickering,†,‡,§ Malgorzata Korbas, Mark J. Hackett,† and Graham N. George*,†,‡,§ †Molecular and Environmental Sciences Research Group, Department of Geological Sciences, University of Saskatchewan, Saskatoon, SK S7N 5E2, Canada ‡Toxicology Centre, University of Saskatchewan, Saskatoon, SK S7N 5B3, Canada Department of Chemistry, University of Saskat...

Elemental Imaging for Pharmaceutical Tablet Formulation Analysis by Micro X-ray Fluorescence

The analysis of the distribution of pharmaceutical materials in tablet formulations, such as drugs and matrix elements, is critical to product performance and is used in such areas as quality control, impurity testing, and process monitoring. Recently imaging techniques, such as Raman, near-IR, and fluorescence imaging, have become popular for “visualization” of pharmaceutical formulations, all...