340 IN-VIVO IMAGING OF CARTILAGE DEGENERATION USING μCT-ARTHROGRAPHY
نویسندگان
چکیده
منابع مشابه
In-Vivo Imaging of Cartilage Degeneration with Micro-CT
In-vivo evaluation of cartilage degeneration in small animals would be extremely useful for studying the aetiology and treatment of osteoarthritis. Currently, delayed gadolinium enhanced MRI of Cartilage (dGEMRIC) has shown to provide proteoglycan distribution by the diffusion of the contrast agent GdDPTPA in the cartilage, specifically at locations where loss of proteoglycans occurs [1]. A sim...
متن کاملDelayed Computed Tomography Arthrography of Human Knee Cartilage In Vivo
OBJECTIVE We investigated the feasibility of delayed computed tomography (CT) arthrography for evaluation of human knee cartilage in vivo. Especially, the diffusion of contrast agent out of the joint space and the optimal time points for imaging were determined. DESIGN Two patients were imaged using delayed CT arthrography and delayed gadolinium-enhanced magnetic resonance imaging of cartilag...
متن کاملImpaired ossification coupled with accelerated cartilage degeneration in developmental dysplasia of the hip: evidences from μCT arthrography in a rat model
BACKGROUND Developmental dysplasia of the hip (DDH) always leads to cartilage degeneration and osteoarthritis of the hip joint. However, the diagnosis of early cartilage degeneration in DDH is still a clinical challenge. This study aims to investigate the dynamic changes of bone and cartilage in the hip of a rat model of DDH and to explore the potential application of microcomputed tomography (...
متن کاملUltra-High Resolution Angiogenesis Imaging using μCT
Aims As a classical hallmark of cancer, angiogenesis is essential for enabling tumors to grow beyond a size of 1-2 mm. Therefore, the visualization and quantification of functional tumor blood vessels within tumors is essential for assessing treatment responses to anti-angiogenic therapies. In experiments using tumor xenografts, anti-angiogenic effects are generally evaluated by immunohistochem...
متن کاملMagnetic Resonance Imaging Based Evaluation of Articular Cartilage Degeneration
Introduction: In-vivo magnetic resonance imaging(MRI) can potentially be used to determine structural changes in articular cartilage of the knee. Water, the dominant component in articular cartilage, is present in both free(70%) and bound form. Bound water is present in collagen fibrils comprising 1020% of the cartilage. Studies indicate that T2 – the proton spin-spin relaxation time parameter ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2007
ISSN: 1063-4584
DOI: 10.1016/s1063-4584(07)61971-2