281 Working towards an age appropriate annual review

Working Towards an Appropriate Use of Ibuprofen in Children: An Evidence-Based Appraisal

Ibuprofen is the most widely used non-steroidal anti-inflammatory drug (NSAID) for the treatment of inflammation, mild-to-moderate pain and fever in children, and is the only NSAID approved for use in children aged ≥3 months. Its efficacy and safety profile have led to its increasing use in paediatric care, even without medical prescription. However, an increase of suspected adverse reactions t...

Alternative Design Scholarship: Working Toward Appropriate Design

Design scholars from diverse fields have attempted to assist marginalized social groups by redirecting design thinking toward their needs. By offering alternatives to dominant design activities, “alternative design” scholarship seeks to understand how unequal power relations are embodied in, and result from, mainstream design practice and products. Alternative design scholars analyze how techno...

Towards a sustainable healthy working life: associations between chronological age, functional age and work outcomes.

BACKGROUND The aims of this study were: (i) to determine the relation between chronological and functional age; (ii) to examine the association between chronological age and work outcomes; and (iii) to examine the association between functional age and work outcomes. An overview of the most reported work outcomes is outlined. METHODS Chronological age refers to the calendar age; functional ag...

An Age Old Problem: Exploring Options for Working with Older People Literature Review

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This study investigated the metabolism of salvianolic acid A (SAA) both in vivo and in vitro. Liquid chromatography–mass spectrometry analysis of drug-containing rat bile samples and bile samples hydrolyzed by glucuronidase revealed a series of methylated conjugates of SAA and its glucuronides, as well as the predominance of the methylation pathway of SAA in rats. For the first time, four major...