28 Radiation Chemistry in Space

Radiation Physics and Chemistry

We review an atomic resolution imaging method based on the analysis of the fine structure in X-ray absorption anisotropy, which results from incident beam diffraction. For a polychromatic X-ray beam, due to the suppression of higher order diffraction fringes, X-ray absorption anisotropy patterns can be interpreted as distorted real-space projections of the atomic structure around absorbing atom...

Radiation chemistry: Radical water.

I onizing radiation is known to be harmful to living organisms because it creates reactive radicals and charged species. In particular, highly energetic X-rays that ionize by removing one of the innermost (core) electrons of an atom lead to a cascade of events that must be better characterized if we are to fully understand their toxic effects 1. Writing in Nature Chemistry, Petr Slavíček, Bernd...

Expanding medicinal chemistry space.

Clinically useful drugs target a relatively small number of proteins that lie within a clearly defined and chemically accessible space. However, many high value biological targets lie outside this chemical space, and an ability to access such 'intractable' targets not amenable to traditional small molecule intervention would expand treatment options and be a major boost for patients and the pha...

Radiation protection in space.

The challenge for planning radiation protection in space is to estimate the risk of events of low probability after low levels of irradiation. This work has revealed many gaps in our knowledge that require further study. Despite investigations of several irradiated populations, the atomic-bomb survivors remain the primary basis for estimating the risk of ionizing radiation. Compared with previo...

Radiation chemistry and oxidative stress