256 NT-proBNP diagnostic value in diagnosis of systolic dysfunction is well documented, however in diastolic dysfunction this value is not clear
نویسندگان
چکیده
منابع مشابه
Do plasma levels of brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) increase in diastolic dysfunction as well as in systolic dysfunction?
fter the structure of atrial natriuretic peptide was established,1 a Japanese group isolated the brain (also known as B-type) natriuretic peptide (BNP) from porcine brain extracts in 1988 by monitoring the relaxant activity of the chick rectum.2 Subsequent studies demonstrated that BNP is a cardiac hormone that is mainly expressed in the heart, where its concentration is considerably higher tha...
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The misinterpretation and misuse of p-value have been increasing for decades. In March 2016, the American Statistical Association released a statement to warn about the use and interpretation of p-value. In this study, we provided a definition and discussion of p-value and emphasized the importance of its accurate interpretation.
متن کاملUtility of N terminal pro brain natriuretic peptide in elderly patients.
OBJECTIVE To evaluate the utility of N terminal pro brain natriuretic peptide (NT-proBNP) as a diagnostic marker for diastolic dysfunction or failure, systolic dysfunction, and significant valve disorders in patients over 75 years. DESIGN Cohort study. SETTING Outpatient echocardiography service in a district general hospital. PARTICIPANTS 100 consecutive patients. MAIN OUTCOME MEASURES...
متن کاملNT-proBNP and BNP values in cardiac patients with different degree of left ventricular systolic dysfunction.
We investigated the performance of brain natriuretic peptides (BNP and NT-proBNP) in detecting various degrees of left ventricular systolic dysfunction. The NT-proBNP assay (Roche) and the BNP assay (Bayer Shionoria) were performed in 46 patients (mean age 50 years; range 20-79 years) with various types of heart disease (chronic heart failure due to coronary artery disease, cardiomyopathy, acqu...
متن کاملNT-proBNP can be used to detect right ventricular systolic dysfunction in pulmonary hypertension.
Right ventricular systolic dysfunction (RVSD) at baseline (pre-treatment) predicts early death in patients with pulmonary hypertension (PH). However, RVSD can only be detected reliably by prohibitively invasive or expensive techniques. N-terminal B-type natriuretic peptide concentration ([NT-proBNP]) correlates with RV function in PH; however, an [NT-proBNP] threshold that indicates RVSD in ind...
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ژورنال
عنوان ژورنال: European Journal of Echocardiography
سال: 2006
ISSN: 1525-2167
DOI: 10.1016/s1525-2167(06)60106-6