24P Establishment of patient-derived xenografts from malignant pleural effusion using NOG mice
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چکیده
منابع مشابه
Establishment of patient-derived cancer xenografts in immunodeficient NOG mice
Viable and stable human cancer cell lines and animal models combined with adequate clinical information are essential for future advances in cancer research and patient care. Conventional in vitro cancer cell lines are commonly available; however, they lack detailed information on the patient from which they originate, including disease phenotype and drug sensitivity. Patient-derived xenografts...
متن کاملEstablishment of Patient-derived Xenografts in Mice.
Patient-derived xenograft (PDX) models for cancer research have recently attracted considerable attention in both the academy and industry (Hidalgo et al., 2014; Wilding and Bodmer, 2014). PDX models have been developed from different tumor types including lung cancer to improve the drug development process. These models are used for pre-clinical drug evaluation and can be used for the predicti...
متن کاملMalignant pleural effusion.
Malignant pleural effusion (MPE) refers to the presence of neoplastic cells in the pleural fluid. Approximately 40 000 people per year in the UK are affected by MPE and it is associated with significant morbidity and an overall poor prognosis. Management should be prompt and care plans should be individualized and involve a multidisciplinary team of healthcare professionals. This article review...
متن کاملMalignant pleural effusion.
Kathleen Shuey, MS, RN, AOCN®, APRN, BC, is an associate director at US Oncology in Houston, TX, and Yvette Payne, MSN, MBA, RN, APN, is an associate director of Clinical Affairs–Oncology at Ortho Biotech Clinical Affairs, LLC, in Tampa, FL. (Mention of specifi c products and opinions related to those products do not indicate or imply endorsement by the Clinical Journal of Oncology Nursing or t...
متن کاملMalignant pleural effusion from prostate adenocarcinoma
Prostate adenocarcinoma is the most common newly diagnosed cancer in males. Pulmonary and pleural metastasis are not uncommon on autopsy, but malignant effusions are not common clinical findings. There are no current recommendations to guide prostate specific antigen level assessment in pleural fluid. A 73 yo w/prostate cancer presented with complaints of subacute worsening of exertional dyspne...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(21)00185-x