24 Resolution of Discrepant Results in Serum Protein Electrophoresis and Immunofixation Electrophoresis
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چکیده
منابع مشابه
Serum protein electrophoresis and immunofixation by a semiautomated electrophoresis system.
Semiautomated agarose electrophoresis and immunofixation performed with Hydrasys-Hyrys (Sebia) were compared with conventional, manually performed methods, including cellulose acetate electrophoresis, immunoelectrophoresis, and immunofixation. Reference intervals for agarose electrophoresis with Hydrasys-Hyrys were determined. Within-run imprecision (CV) for fraction quantitation with the semia...
متن کاملDetection by immunofixation of M proteins in hypogammaglobulinemic patients with normal serum protein electrophoresis results.
Serum protein electrophoresis (SPE) demonstrates a monoclonal protein as an M spike in the majority of patients with monoclonal gammopathies. However, in patients with an apparently normal SPE pattern or hypogammaglobulinemia, immunofixation electrophoresis (IFE) can reveal an M protein. We undertook this study to determine the yield of reflex IFE testing in patients with hypogammaglobulinemia ...
متن کاملSensitivity of immunofixation electrophoresis for detecting IgM paraproteins in serum.
Detection and characterization of small IgM paraproteins by immunoelectrophoresis are often difficult because of (a) slow diffusion of the macromolecular immunoglobulin, and (b) the obscuring of the light chain, especially kappa, by the light chains of background polyclonal immunoglobulin (the "umbrella effect"). Various methods of sample pretreatment have been tried in an attempt to overcome t...
متن کاملUrine protein electrophoresis and immunofixation electrophoresis supplement one another in characterizing proteinuria.
Urine protein electrophoresis (UPE) is often considered to have limited usefulness in evaluating proteinuria that is not associated with gammopathies. Unusual protein bands that are detected by UPE are commonly characterized by immunofixation electrophoresis (IFE). In this paper, electrophoretic gel patterns are shown to illustrate the greater sensitivity of IFE, compared to UPE. However, UPE r...
متن کاملSerum Protein Electrophoresis
electrophoresis for detection of DNA point mutations. Journal of Chromatography B 697: 195}205. Righetti PG and GelR C (1998) Analysis of clinicallyrelevant, diagnostic DNA by capillary zone and double-gradient gel slab electrophoresis. Journal of Chromatography A 806: 97}112. Thormann W (1997) Drug monitoring by capillary electrophoresis. In Wong SHY, Sunshine I (Eds) Analytical Therapeutic Dr...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2018
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/aqx115.023