204Voriconazole Restriction in Addition to Therapeutic Drug Monitoring (TDM) Protocol Results in Optimized Dosing
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204Voriconazole Restriction in Addition to Therapeutic Drug Monitoring (TDM) Protocol Results in Optimized Dosing
204. Voriconazole Restriction in Addition to Therapeutic Drug Monitoring (TDM) Protocol Results in Optimized Dosing Natasha Pettit, PharmD; Zhe Han, PharmD; Mildred Vicente, PharmD; Emily Landon, MD; Jennifer Pisano, MD; Allison H. Bartlett, MD, MS; Pharmacy Services, University of Chicago Medicine, Chicago, IL; Pharmacy Services, University of Chicago Medicine, Chicago, IL; Infectious Diseases...
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Background. PCZ is a broad spectrum azole antifungal used for prophylaxis in high risk patients and treatment of invasive fungal infections, with activity against Candida spp., Aspergillus spp., and other invasive molds. TDM of PCZ is recommended to ensure efficacy with a goal therapeutic serum concentration (TC) of >700 ng/ml, some studies support a goal of >500 ng/ml for prophylaxis. Two oral...
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Methods In this prospective, open labelled study, pregnant HIVpositive women received ATV/r as part of their routine pre-natal care. Demographic and clinical data were collected, and ATV plasma concentrations [ATV] were determined in the first (T1) and/or second (T2) and/or third (T3) trimester using HPLC-MS/MS (LLQ = 0.05 μg/mL). Postpartum (PP) sampling was performed where applicable. Antepar...
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هدف اصلی این تحقیق مقایسه و تمایز بین روشها و استراتژیهای خاص برای درک مطلب بهتر در زبان مادری و زبان دوم بوده است. در قدم اول میزان توانایی افراد در درک مطلب فارسی و انگلیسی اندازه گیری و سپس رده بندی شد. همچنین از دانش آموزان خواسته شد که در مورد روشها و استراتژیهایی که برای درک مطلب بهتر به کار برده بودند توضیح دهند. نتیجه این مرحله از تحقیق نشان داد که دانشجویان برای درک مطلب مطلوب در زبان ...
15 صفحه اولPotential of Surface Enhanced Raman Spectroscopy (SERS) in Therapeutic Drug Monitoring (TDM). A Critical Review
Surface-Enhanced Raman Spectroscopy (SERS) is a label-free technique that enables quick monitoring of substances at low concentrations in biological matrices. These advantages make it an attractive tool for the development of point-of-care tests suitable for Therapeutic Drug Monitoring (TDM) of drugs with a narrow therapeutic window, such as chemotherapeutic drugs, immunosuppressants, and vario...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2014
ISSN: 2328-8957
DOI: 10.1093/ofid/ofu052.70