2-Propargylamino-6-(trifluoromethoxy)benzo[d]thiazoles in an alkyne-azide click reaction with pharmacologically active fragments
نویسندگان
چکیده
A synthetic approach to the modification of drug Riluzole with pharmacologically active fragments (adamantane, carbazole, tetrahydrocarbazole, γ-carboline, and phenothiazine) was proposed, which is based on copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition azide-containing pharmacophores alkyne-containing derivatives Riluzole.
منابع مشابه
Clusters for alkyne-azide click reactions.
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ژورنال
عنوان ژورنال: Russian Chemical Bulletin
سال: 2021
ISSN: ['1573-9171', '1066-5285']
DOI: https://doi.org/10.1007/s11172-021-3113-7