منابع مشابه
Reproductive toxicology. p-Nitrobenzoic acid.
Background. Hox genes are implicated in hematopoietic stem cell (HSC) regulation as well as in leukemia development through translocation with the nucleoporin gene NUP98. Interestingly, an engineered NUP98-HOXA10 (NA10) fusion can induce a several hundred-fold expansion of HSCs in vitro and NA10 and the AML-associated fusion gene NUP98-HOXD13 (ND13) have a virtually indistinguishable ability to...
متن کاملThe Modffication of Cholinesterase Activity by 5 , 5 ' - Dithiobis - ( 2 - nitrobenzoic Acid ) included in the Coupled Spectrophotometric Assay
1. Compared with the acetylcholinesterase assay carried out in the absence of a dithiol, the presence of 5,5'-dithiobis-(2-nitrobenzoic acid) caused marked activation, 6,6'dithiodinicotinic acid and 2,2'-dithiobis-(5-nitropyridine) less so and 2,2'-dithiodipyridine (aldrithiol-2) had no effect at all. Measurements are further complicated in that the 5-thio-2-nitrobenzoate ion also appears to in...
متن کاملRole of 5-thio-(2-nitrobenzoic acid)-capped gold nanoparticles in the sensing of chromium(vi): remover and sensor.
This study describes a simple, rapid method for sensing Cr(vi) using 5-thio-(2-nitrobenzoic acid) modified gold nanoparticles (TNBA-AuNPs) as a remover for Cr(iii) and as a sensor for Cr(vi). We discovered that TNBA-AuNPs were dispersed in the presence of Cr(vi), whereas Cr(iii) induced the aggregation of TNBA-AuNPs. Due to this phenomenon, TNBA-AuNPs can be used as a sorbent material for the r...
متن کاملOn the reactivity of metallothioneins with 5,5'-dithiobis-(2-nitrobenzoic acid).
Rat liver and horse kidney metallothioneins react with 5,5'-dithiobis-(2-nitrobenzoic acid) (Nbs2) to release 5-thio-2-nitrobenzoate and metal ions. The reactions are slow and exhibit biphasic kinetics with each process having an empirical rate law of the form: rate - k[RSM] X [Nbs2] + k'[RSM], where RSM represents mental-bound thiolate groups. The pseudo-first-order rates are insensitive to pH...
متن کاملMechanism of the inactivation of guinea pig liver transglutaminase by 5,5'-dithiobis-(2-nitrobenzoic acid).
Reaction of 5,5’-dithiobis(24trobenzoic acid) (DTNB) with transglutaminase in the absence of calcium ion results in losses in the transferase and hydrolysis activities of the enzyme toward the substrate, benzyloxycarbonyl-L-glutaminylglycine (Z-L-glutaminylglycine). These activities are reduced 70 to 100% by reaction with 1 to 1.5 eq of DTNB. The calcium-dependent esterase activity of transglut...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2010
ISSN: 1600-5368
DOI: 10.1107/s160053681001946x