منابع مشابه
Lipoprotein-associated Phospholipase A2: Effects of Low Density Lipoprotein Apheresis
In addition to hypercholesterolemia, chronic arterial inflammation has been shown to be strongly associated with atherosclerosis and cardiovascular disease (CVD) [1]. The accumulation and oxidation of LDL within the intima trigger inflammatory processes within the vessel wall. Certain markers of inflammation, such as C-reactive protein (CRP), soluble CD40 ligand (sCD40L), oxidized LDL, and lipo...
متن کاملCoronary plaque regression: role of low density lipoprotein-apheresis.
It has been proven beyond all reasonable doubt that lowering the level of low density lipoprotein cholesterol (LDL-C) reduces cardiovascular morbidity and mortality (1–7). This benefit has been demonstrated in both a primary and secondary prevention setting and has been observed in hard end point and in regression studies. Benefits are apparent both in subjects with hypercholesterolemia and in ...
متن کاملMathematical Model for Low Density Lipoprotein (LDL) Endocytosis by Hepatocytes
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease. LDL particles are removed from the blood by a process known as receptor-mediated endocytosis, which occurs mainly in the liver. A series of classical experiments delineated the major steps in the endocytotic process; apolipoprotein B-100...
متن کاملLow-density lipoprotein (LDL)-antioxidant biflavonoids from Garcinia madruno.
Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu²⁺, was studied by means of a TBARS assay. The antioxidan...
متن کاملDiscordance of low-density lipoprotein (LDL) cholesterol with alternative LDL-related measures and future coronary events.
BACKGROUND Low-density lipoprotein cholesterol (LDL-C) is the traditional measure of risk attributable to LDL. Non-high-density lipoprotein cholesterol (NHDL-C), apolipoprotein B (apoB), and LDL particle number (LDL-P) are alternative measures of LDL-related risk. However, the clinical utility of these measures may only become apparent among individuals for whom levels are inconsistent (discord...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2009
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.98.1069