2-(2-(4-Methoxyphenyl)furo[3,2-h]quinolin-3-yl)acetic Acid
نویسندگان
چکیده
A simple and efficient protocol for the synthesis of previously unknown 2-(2-(4-methoxyphenyl)furo[3,2-h]quinolin-3-yl)acetic acid was elaborated. The suggested method is based on telescoped multicomponent reaction 8-hydroxyquinoline, 4-methylglyoxal, Meldrum’s acid. studied process includes initial interaction starting compounds in MeCN followed by intramolecular cyclization to target product refluxing acetic advantage this approach application readily available materials, atom economy, a work-up procedure. structure synthesized furylacetic derivative proven 1H, 13C, 2D-NMR, IR spectroscopy, high-resolution mass spectrometry.
منابع مشابه
SYNTHESIS OF 3-ARYLMETHYL-4- THIAZOLIDINE-CARBOXYLIC ACID-2-ONES AND 2-THIONES
Barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of Lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. Their reduction with zinc and hydrochloric acid in methanol yielded the Narylmethylcysteines ?9a-c?. These can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?Reaction of N, N'-carbonyl diimidazole (Im C...
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barium salts of dibenzylidene cystines 8a-c were obtained from the reaction of lcystine with benzaldehyde or its derivatives in the presence of barium hydroxide. their reduction with zinc and hydrochloric acid in methanol yielded the narylmethylcysteines ?9a-c?. these can, in turn, be converted by esterification into the methyl esters ?10 a-c. ?reaction of n, n'-carbonyl diimidazole (im co...
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ژورنال
عنوان ژورنال: Molbank
سال: 2022
ISSN: ['1422-8599']
DOI: https://doi.org/10.3390/m1315