(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-Aminobutyrate Hydrochloride

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(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 4-Aminobutyrate Hydrochloride

The title ester (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 4-aminobutyrate hydrochloride was obtained in 96% yield via Steglich esterification. The structure of the target compound was established by FTIR, HR-MS, 1H-NMR, 13C-NMR spectral analysis, and single crystal X-ray diffraction study. Single crystals of the title ester suitable for X-ray investigation were obtained by slow evaporation of t...

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Chiral 4-[(2-isopropyl-5-methylcyclohexyl)oxo]-4oxobutanoic acid reacts with substituted anilines to produce amides 1-6 in high yields. Resulted amides 1-6 were investigated for their antifungal and antibacterial activities. Compounds 2 (96.5%) against Aspergillus fumigatus and 6 (93.7%) against Helminthosporium sativum demonstrated excellent activities. However, compounds 3 (37.6%) against Bac...

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In the title compound, C7H12N2OS, the 2-sulfanylideneimidazolidin-4-one moiety is nearly planar, with a maximum deviation of 0.054 (2) Å. In the crystal, a pair of N-H⋯O hydrogen bonds and a pair of N-H⋯S hydrogen bonds each form a centrosymmetric ring with an R 2 (2)(8) graph-set motif. The enanti-omeric R and S mol-ecules are alternately linked into a tape along [1-10] via these pairs of hydr...

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ژورنال

عنوان ژورنال: Molbank

سال: 2017

ISSN: 1422-8599

DOI: 10.3390/m956