1914 - Decepción de Theodor Axenfeld

Emil Theodor Kocher 1841 – 1917

The Axenfeld syndrome and the Rieger syndrome.

A family is reported in which both the syndrome of Axenfeld and the eye malformations of the syndrome of Rieger occur, indicating that both may be expressions of the same gene. We also review the associated anomalies already reported, emphasise their high incidence, suggest that these are not accidental associations, and propose some possible explanations for the high incidence.

Dmd053199 1914..1922

Naturally occurring furanocoumarin compounds psoralen (PRN) and isopsoralen (IPRN) are bioactive constituents found in herbaceous plants. They are widely used as active ingredients in several Chinese herbal medicines. In this study, the CYP1A2 inhibitory potential of PRN and IPRN was investigated in rats in vitro and in vivo as well as in human liver microsomes. Both compounds exhibited reversi...

Max Perutz (1914–2002)

Become a scientist, Ernest Rutherford would urge his friends, for then you will never be old, you will remain all your life a child at play. So it proved for the evergreen Max Perutz, who did his last experiment only weeks before he died at the fine age of eighty-seven. Perutz embraced Noël Coward's dictum that 'work is fun, work is much more fun than fun'. In an eventful life, beset in its ear...

Theodor Förster: a giant of modern photochemistry.

The year 2011 marks the centenary of the birth of Theodor Fçrster, one of the giants of modern photochemistry. This issue is a celebration of Fçrster’s scientific achievements, and equally importantly, the science that has been enabled by his discoveries. His contributions are key to the understanding of important problems in excited-state photochemical reactions and the understanding of organi...