18S rRNA processing requires base pairings of snR30 H/ACA snoRNA to eukaryote-specific 18S sequences
نویسندگان
چکیده
منابع مشابه
18S rRNA processing requires base pairings of snR30 H/ACA snoRNA to eukaryote-specific 18S sequences
The H/ACA RNAs represent an abundant, evolutionarily conserved and functionally diverse class of non-coding RNAs. Many H/ACA RNAs direct pseudouridylation of rRNAs and snRNAs, while members of the rapidly growing group of 'orphan' H/ACA RNAs participate in pre-rRNA processing, telomere synthesis and probably, in other nuclear processes. The yeast snR30 'orphan' H/ACA snoRNA has long been known ...
متن کاملU17/snR30 is a ubiquitous snoRNA with two conserved sequence motifs essential for 18S rRNA production.
Saccharomyces cerevisiae snR30 is an essential box H/ACA small nucleolar RNA (snoRNA) required for the processing of 18S rRNA. Here, we show that the previously characterized human, reptilian, amphibian, and fish U17 snoRNAs represent the vertebrate homologues of yeast snR30. We also demonstrate that U17/snR30 is present in the fission yeast Schizosaccharomyces pombe and the unicellular ciliate...
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متن کامل18S rRNA processing requires the RNA helicase-like protein Rrp3.
We report the identification of a new gene, RRP3 (rRNA processing), which is required for pre-rRNA processing. Rrp3 is a 60.9 kDa protein that is required for maturation of the 35S primary transcript of pre-rRNA and is required for cleavages leading to mature 18S RNA. RRP3 was identified in a PCR screen for DEAD box genes. DEAD box genes are part of a large family of proteins homologous to the ...
متن کاملDetection of fungal 18S rRNA sequences in conjunction with marine nematode 18S rRNA amplicons
Free-living nematodes constitute an important component of estuarine and marine benthic ecosystems. Some marine and soil nematodes are known to harbor microbes, including symbiotic bacteria and fungi, in their external cuticle as well as internally. While assessing diversity of marine nematodes from southwest England using molecular approaches, we found evidence of coamplification of fungal 18S...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2009
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2009.79