17-P005 Molecular characterization of neural stem cells in medaka

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17-P005 Molecular characterization of neural stem cells in medaka

While adult neurogenesis in mammals is mainly restricted to two telencephalic zones, in teleost fishes, neurogenesis has been observed in many brain areas. Hence, the medaka (Oryzias latipes) represents an excellent model to study neural stem cells (NSCs). In order to detect NSCs, we have relied on the fact that adult stem cells divide more slowly than quickly amplifying progenitor cells. By us...

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The excessive electrical activity of neurons is reported in many diseases including: Parkinson's disease, Alzheimer's disease, and Epilepsy. Electrical overactivity in hippocampus accelerates the depletion of neural stem cell (NSC) and impairs the neurogenesis in hippocampus. It is believed that neurogenesis in hippocampus improves the cognitive functions. In this experiment, we use kindled mod...

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In Vitro Differentiation of Neural Stem Cells into Noradrenergic-Like Cells

Neural stem cells (NSCs) as a heterogeneous multipotent and self- renewal population are found in different areas in the developing mammalian nervous system, as well as the sub-ventricular zone (SVZ) and the hippocampus of the adult brain. NSCs can give rise to neurons, astrocytes and oligodendrocytes. The aim of this study was to differentiate neural stem cells into noradrenergic–like cells in...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 2009

ISSN: 0925-4773

DOI: 10.1016/j.mod.2009.06.726