149 The distribution of water and ions around nucleic acids
نویسندگان
چکیده
منابع مشابه
Counting the ions surrounding nucleic acids
Nucleic acids are strongly negatively charged, and thus electrostatic interactions-screened by ions in solution-play an important role in governing their ability to fold and participate in biomolecular interactions. The negative charge creates a region, known as the ion atmosphere, in which cation and anion concentrations are perturbed from their bulk values. Ion counting experiments quantify t...
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Using a new method of calculating the effects of excluded volume, the authors evaluate the distribution of counterions around a charged sphere in thermal equilibrium. In regions of high concentration a saturation of the ion density is found, which is absent in the more conventional Gouy-Chapman model. At the same time the saturation effect of the potential (a property of the Gouy-Chapman model)...
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Scientific Program The following distinguished speakers have already agreed to deliver a lecture: Prof. Bibudgendra Sarkar (TORONTO, CANADA), Prof. James Allan Cowan (COLUMBUS, USA), Prof. Bernard Meunier (CNRS, FRANCE), Prof. Rob Kaptein (UTRECHT, THE NETHERLANDS), Prof. Thomas W. Myers (ROCHE, USA), Prof. Matthias W. Henteze (EMBL GERMANY), Prof. Huguette Pelletier (HOUSTON, USA). In addition...
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Correctly folded into the respective native 3D structure, RNA and DNA are responsible for uncountable key functions in any viable organism. In order to exert their function, metal ion cofactors are closely involved in folding, structure formation and, e.g. in ribozymes, also the catalytic mechanism. The database MINAS, Metal Ions in Nucleic AcidS (http://www.minas.uzh.ch), compiles the detailed...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Structure and Dynamics
سال: 2015
ISSN: 0739-1102,1538-0254
DOI: 10.1080/07391102.2015.1032782