147P Midline crossing grade I to grade III gliomas: Impact of high dose XRT on survival
نویسندگان
چکیده
منابع مشابه
High Grade Gliomas Hg-01. Etoposide Improves Survival in High Grade Glioma: a Meta-analysis
BACKGROUND: Despite standard therapy, high grade gliomas (HGGs) have a very poor prognosis. There are numerous phase I and phase II trials investigating novel agents and multimodal approaches that seek to improve upon survival in these patients. The purpose of this study was to evaluate the therapeutic efficacy of topoisomerase inhibitors in the treatment of HGGs. METHODS: We compared the effic...
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High-grade gliomas are characterized with poor prognosis. To improve the clinical outcome, biomarker is urgently needed for distinguishing oncotarget in high-grade gliomas. Telomere maintenance 2 (TELO2) regulates S-phase checkpoint in cell cycle, and is involved in DNA repair. However, the role of TELO2 in survival outcome of high-grade gliomas is still not yet clarified. This study aims to in...
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The 2016 WHO classification of Tumors of the Central Nervous System brought major conceptual and practical changes in the classification of diffuse gliomas, by combining molecular features and histology into 'integrated' diagnoses. In diffuse gliomas, molecular profiling has thus become essential for nosological purposes, as well as to plan adequate treatment strategies and identify patients su...
متن کاملStereotactic laser ablation of high-grade gliomas.
Evolving research has demonstrated that surgical cytoreduction of a high-grade glial neoplasm is an important factor in improving the prognosis of these difficult tumors. Recent advances in intraoperative imaging have spurred the use of stereotactic laser ablation (laser interstitial thermal therapy [LITT]) for intracranial lesions. Among other targets, laser ablation has been used in the focal...
متن کاملSHOX2 is a Potent Independent Biomarker to Predict Survival of WHO Grade II–III Diffuse Gliomas
BACKGROUND Diffuse gliomas, grades II and III, hereafter called lower-grade gliomas (LGG), have variable, difficult to predict clinical courses, resulting in multiple studies to identify prognostic biomarkers. The purpose of this study was to assess expression or methylation of the homeobox family gene SHOX2 as independent markers for LGG survival. METHODS We downloaded publically available g...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(21)00305-7