منابع مشابه
Reduction and uptake of methylene blue by human erythrocytes.
A thiazine dye reductase has been described in endothelial cells that reduces methylene blue (MB), allowing its uptake into cells. Because a different mechanism of MB uptake in human erythrocytes has been proposed, we measured MB uptake and reduction in this cell type. Oxidized MB (MB(+)) stimulated reduction of extracellular ferricyanide in a time- and concentration-dependent manner, reflectin...
متن کاملUptake of Some Quaternary Ammonium Ions by Human Erythrocytes
I N T R O D U C T I O N Biochemical a n d nu t r i t iona l studies l ong ago suggested t h a t a t least some of t h e cells w i th in the gastrointes t inal t r a c t a r e p e r m e a b l e to some q u a t e r n a r y a m m o n i u m ions. F o r example , w h e n chol ine was fed to ra t s its pa r t i c ipa t ion in the process of t r ansme thy la t i on wi th in tissues was shown (1). M o ...
متن کاملPathways of adenine nucleotide catabolism in erythrocytes.
The exact pathway whereby the initial catabolism of the adenine nucleotides proceeds from AMP and the possibility of a recycling of adenosine were investigated in human erythrocytes. Adenine nucleotide catabolism, reflected by the production of hypoxanthine, is very slow under physiologic conditions and can be greatly increased by suppression of glucose or alkalinization of the medium. Experime...
متن کاملUptake and antioxidant effects of ergothioneine in human erythrocytes.
Ergothioneine is a fungal metabolite that may have antioxidant functions in mammalian cells. Although it accumulates to low millimolar concentrations in liver and other tissues, it is not thought to be taken up by mature erythrocytes. During a study of the function of ergothioneine as an antioxidant in human erythrocytes, we found that these cells do take up ergothioneine from the surrounding m...
متن کاملNitrite uptake and metabolism and oxidant stress in human erythrocytes.
Nitric oxide, when released into the bloodstream, is quickly scavenged by Hb in erythrocytes or oxidized to nitrite. Nitrite can also enter erythrocytes and oxidize Hb. The goals of this work were to determine the mechanism of erythrocyte nitrite uptake and whether this uptake causes oxidant stress in these cells. Erythrocytes took up 0.8 mM nitrite with a half-time of 11 min. Nitrite uptake wa...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1988
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198807000-00158