[ 11 C]Carfentanil Binds Preferentially to μ-Opioid Receptor Subtype 1 Compared to Subtype 2
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منابع مشابه
Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats.
The purpose of this study was to examine in vivo the importance of angiotensin subtype 1 (AT1) versus subtype 2 (AT2) receptors in spontaneously hypertensive (hypertensive) versus normotensive Wistar-Kyoto (control) rats. Intravenous infusions of DuP 753, a selective AT1 receptor antagonist, abolished the pressor responses to intravenous infusions of angiotensin II in both strains, and the pote...
متن کاملAssignment of porcine serotonin receptor subtype 2 alpha and endothelin-B receptor to chromosome 11 by linkage analysis.
Genus and Species. Sus scrofa. Locus. Pig serotonin receptor subtype 2 alpha ( HTR2A) and pig endothelin-B receptor ( EDNRB) . Source and Description of Primers. Heterologous primers for EDNRB were obtained from Leslie Lyons through the CATS project (Lyons et al., 1997) and primers for HTR2A were designed from highly conserved human (M86841) and mouse sequences (X72222). Primers ( EDNRB forward...
متن کاملa1-Adrenergic Receptor Subtype
Background. Recent advances in adrenergic pharmacology have made possible the identification of a1-adrenergic receptor subtypes using the specific blockers chloroethylcionidine and WB 4101. Methods and Results. In the present study, we used these two blockers to determine the mechanisms responsible for automatic rhythms occurring during simulated ischemia and reperfusion of isolated canine Purk...
متن کاملRoles of Opioid Receptor Subtype in the Spinal Antinociception of Selective Cyclooxygenase 2 Inhibitor
BACKGROUND Selective inhibitors of cyclooxygenase (COX)-2 are commonly used analgesics in various pain conditions. Although their actions are largely thought to be mediated by the blockade of prostaglandin (PG) biosynthesis, evidences suggesting endogenous opioid peptide link in spinal antinociception of COX inhibitor have been reported. We investigated the roles of opioid receptor subtypes in ...
متن کاملKappa2 opioid receptor subtype binding requires the presence of the DOR-1 gene.
Over the past several years substantial evidence has documented that opioid receptor homo- and heterodimers form in cell lines expressing one or more of the opioid receptors. We used opioid receptor knockout mice to determine whether in vivo pharmacological characteristics of kappa1 and kappa2 opioid receptors changed following knockout of specific opioid receptors. Using displacement of the ge...
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ژورنال
عنوان ژورنال: Molecular Imaging
سال: 2015
ISSN: 1536-0121,1536-0121
DOI: 10.2310/7290.2015.00019