1083 – Gut Sensing of Nutrient Caloric Content
نویسندگان
چکیده
منابع مشابه
From gut nutrient sensing to nutrient perception: a cooperative role involving CCK and 5-HT?
GUT-BRAIN AXIS INTERPLAY REMAINS a major question in physiology. The release of 5-HT by endocrine cells was previously demonstrated to respond to different stimuli including pressure sensors and sodium-glucose cotransporter, whereas CCK release responds to apolipoprotein A-IV and Pept1 activation. The paper from Savastano, Hayes, and Covasa in this issue of AJP-Regulatory, Integrative and Compa...
متن کاملNutrient modulation of intestinal gas dynamics in healthy humans: dependence on caloric content and meal consistency.
The actions of nutrients on gut transit of liquids and solids have been extensively studied, but the effects of meal ingestion on intestinal gas flow are unexplored. We hypothesized that meals of varying caloric content and consistency modulate gas transit to different degrees. Nine healthy volunteers underwent jejunal perfusion of physiological gas mixtures at 12 ml.min(-1).3 h, with ingestion...
متن کاملCaloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration
Mitochondrial activity progressively declines during ageing and in many neurodegenerative diseases. Caloric restriction (CR) has been suggested as a dietary intervention that is able to postpone the detrimental aspects of aging as it ameliorates mitochondrial performance. This effect is partially due to increased mitochondrial biogenesis. The nutrient-sensing PGC-1α is a transcriptional coactiv...
متن کاملPostoral glucose sensing, not caloric content, determines sugar reward in C57BL/6J mice.
Recent studies suggest that because of their energy value, sugars are more rewarding than non-caloric sweeteners. However, intragastric infusion data indicate that sugars differ in their postoral appetite-stimulating effects. We therefore compared the preference for isocaloric 8% sucrose, glucose, and fructose solutions with that of a non-caloric sweetener solution (0.8% sucralose) in C57BL/6J ...
متن کاملRole of gut nutrient sensing in stimulating appetite and conditioning food preferences.
The discovery of taste and nutrient receptors (chemosensors) in the gut has led to intensive research on their functions. Whereas oral sugar, fat, and umami taste receptors stimulate nutrient appetite, these and other chemosensors in the gut have been linked to digestive, metabolic, and satiating effects that influence nutrient utilization and inhibit appetite. Gut chemosensors may have an addi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gastroenterology
سال: 2019
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)37368-8