منابع مشابه
THE SYNTHESES OF 1- [[2- AMINO -1 - (HYDROXYMETHYL) ETHOXY] METHYL] URACIL AND 1, 3-BIS (2- HALOETHOXYMETHYL) PYRIMIDINE
The syntheses of the title compounds are described. 1- [[2- Amino -1 - (hydroxymethyl) ethoxy] methyl] uracil exhibitslittleactivity against herpesviruses (HSV) in vivo
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Six new homologues of the 3-alkanoyl-5-hydroxymethyl tetronic acid (1 ~6) (Scheme 1) have been identified in extracts of the Actinomycete strain DSM7357 as inhibitors of HIV-1 protease. In the preceding paper1} we described the fermentation, isolation and biological properties of these secondary metabolites 1 ~6. The length and substitution pattern of the alkanoyl side chain of the tetronic aci...
متن کامل1-Hydroxymethyl-1-methylethanaminium chloride
The asymmetric unit of the title compound, C(4)H(12)NO(+)·Cl(-), contains two independent ion pairs. Weak intra-molecular C-H⋯O and N-H⋯O hydrogen bonds result in the formation of three five-membered rings, which have envelope conformations. The crystal structure contains intermolecular O-H⋯Cl, N-H⋯O, N-H⋯Cl and O-H⋯O hydrogen bonds.
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There are two mol-ecules in the asymmetric unit of the title compound, C(15)H(16)N(2)O(4)S, both of which are stabilized by an intra-molecular O-H⋯N hydrogen bond. Inter-molecular N-H⋯O hydrogen bonds lead to [101] chains of mol-ecules in the crystal structure.
متن کاملThe effect of 3-(5′-hydroxymethyl-2’-furyl)-1-benzylindazole (YC-1) on cell viability under hypoxia
PURPOSE The synthetic compound 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) reduces the protein stability of hypoxia-inducible factor (HIF)-1α and can serve as a potential anticancer agent. Our previous study elucidated that YC-1 decreased the protein level of HIF-1α and inhibited cell proliferation under normoxic conditions. In the present study, we explored the inhibitory effect of Y...
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ژورنال
عنوان ژورنال: Molecules
سال: 1999
ISSN: 1420-3049
DOI: 10.3390/m116