089 Regression of myocardial oedema is related to improvement in myocardial contractility following reperfused acute myocardial infarction

Recovery of regional myocardial function and myocardial oedema following reperfused acute myocardial infarction

We investigated the relationship between myocardial oedema and recovery of regional myocardial function in patients with acute reperfused myocardial infarction (MI). Early after acute MI, oedema in the peri-infarct zone, as delineated by T2 weighted (T2w) cardiovascular magnetic resonance (CMR) imaging, demonstrated significantly reduced strain as compared to remote myocardium. The recovery of ...

Translation of Methdology used in Human Myocardial Imaging to a Sheep Model of Acute Myocardial Infarction

Background: Pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. The aim of this study was to evaluate whether SPECT/CT myocardial perfusion imaging (MPI) could be used for assessing sheep myocardium following an acute myocardial infarction (MI) and response to int...

Cardiovascular magnetic resonance imaging of myocardial oedema following acute myocardial infarction: Is whole heart coverage necessary?

BACKGROUND AAR measurement is useful when assessing the efficacy of reperfusion therapy and novel cardioprotective agents after myocardial infarction. Multi-slice (Typically 10-12) T2-STIR has been used widely for its measurement, typically with a short axis stack (SAX) covering the entire left ventricle, which can result in long acquisition times and multiple breath holds. This study sought to...

Rapid Diagnosis of Acute Myocardial Infarction

To improve the specificity of biochemical markers of myocardial infarction (MI) a method to measure cardiac troponin-I (CTn-I) was developed. CTn-I is a protein unique to cardiac muscle and is released after MI. Consecutive 150 patients admitted to the coronary care unit was studied. Value of CTn-I was determined in all samples. CTn-I concentration in the MI patients group was increased com...

Myocardial Hemorrhage After Acute Reperfused ST-Segment–Elevation Myocardial Infarction