0724 EXCESSIVE DAYTIME SLEEPINESS PREDICTS NEURODEGENERATION IN IDIOPATHIC REM SLEEP BEHAVIOR DISORDER
نویسندگان
چکیده
منابع مشابه
Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.
OBJECTIVE To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease. METHODS The Epworth Sleepiness Scale (ESS) and its determinants were compared at the time of a video-polysomnography for an RBD diagnosis in patients with idiopathic RBD, in patients with Parkinson disea...
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OBJECTIVES Patients with idiopathic REM sleep behavior disorder (IRBD) are at risk for developing Parkinson disease (PD) and dementia with Lewy bodies (DLB). We aimed to identify functional brain imaging patterns predicting the emergence of PD and DLB in patients with IRBD, using SPECT with (99m)Tc-ethylene cysteinate dimer (ECD). METHODS Twenty patients with IRBD were scanned at baseline dur...
متن کاملSeverity of REM atonia loss in idiopathic REM sleep behavior disorder predicts Parkinson disease.
BACKGROUND Over 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson disease (PD) or dementia. At present, there is no way to predict who will develop disease. Since polysomnography is performed in all patients with idiopathic RBD at diagnosis, there is an opportunity to analyze if baseline sleep variables predict eventual neurodegenerative disease. METHODS ...
متن کاملClinical Biomarkers of Neurodegeneration in REM Sleep Behavior Disorder
Address for correspondence Yun Kwok Wing, FRCPsych Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR Tel: +852-26367748 Fax: +852-26475321 E-mail: [email protected] Rapid eye movement sleep behavior disorder (RBD) is currently considered as a prodromal stage of α-synucleinopathies neurodegeneration. The update data suggested that over 80%...
متن کاملExcessive daytime sleepiness.
Excessive daytime sleepiness is one of the most common sleep-related patient symptoms, and it affects an estimated 20 percent of the population. Persons with excessive daytime sleepiness are at risk of motor vehicle and work-related incidents, and have poorer health than comparable adults. The most common causes of excessive daytime sleepiness are sleep deprivation, obstructive sleep apnea, and...
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ژورنال
عنوان ژورنال: Sleep
سال: 2017
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleepj/zsx050.723