0362 Sleep Medication Use in Hospitalized Geriatric Patients and Associated Outcomes

Abstract Introduction Disturbances in the diurnal sleep-wake cycles are prevalent within geriatric population, consequently increasing development of insomnia. Although insomnia is commonly treated inpatient setting, many pharmacologic interventions classified as potentially inappropriate medications for defined through Beers Criteria; risk adverse events (AEs) this population. Methods A retrospective review and comparative analysis used treatment (diphenhydramine [DPH], hydroxyzine [HDX], trazodone [TZD]) 121 hospitalized patients (≥65 years old) our facility during month October 2021 was conducted. Multiple regression to identify associations between selected medication use AEs including falls, new or worsening delirium, onset urinary retention. Comparative using individual T-testing groups, Kruskal-Wallis Testing total comparison significance group outcomes. Results Patients with DPH HDX showed significantly higher rates compared TZD (p< 0.001); but no significant difference frequency themselves (p=0.816). 54.8% 57.7% had at least one recorded AE their hospital stay. The most common all groups delirium 31.0%, 38.5%, 15.6% DPH, HDX, respectively. Both falls (4.8% 11.5%) retention (14.3% 7.7%) respectively, whereas neither these AEs. Analysis yielded secondary outcomes constipation occurring only 11.9%. Further, a increase length stay (HLOS) 0.01), not (p=0.755). Conclusion Treatment complex. Use anticholinergic (DPH/HDX) substantially increases increased HLOS, possibly direct result incurred medications. Support (if any)