033. URINE CALPROTECTIN AS DISEASE ACTIVITY AND PROGNOSTIC BIOMARKER IN ANCA-ASSOCIATED VASCULITIS (AAV)
نویسندگان
چکیده
منابع مشابه
Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis
The endothelial-specific Angiopoietin-Tie2 ligand-receptor system is an important regulator of endothelial activation. Binding of angiopoietin-2 (Ang-2) to Tie2 receptor renders the endothelial barrier responsive to pro-inflammatory cytokines. We previously showed that circulating Ang-2 correlated with disease severity in a small cohort of critically ill patients with anti-neutrophil cytoplasmi...
متن کاملDiagnostic Value of Procalcitonin in ANCA-Associated Vasculitis (AAV) to Differentiate Between Disease Activity, Infection and Drug Hypersensitivity
OBJECTIVE Procalcitonin (PCT) is considered to be a specific marker for severe bacterial infections and sepsis. Elevated PCT levels have been reported in active autoimmune diseases without infection. The aim of this study was to assess the diagnostic value of PCT serum levels in ANCA-associated vasculitis (AAV) patients with respect to infection, disease activity and drug fever using a high sen...
متن کاملUrine IgM excretion predicts outcome in ANCA-associated renal vasculitis.
BACKGROUND Renal function at diagnosis is a strong predictor not only of renal survival but also of patient survival of those with anti-neutrophil cytoplasmic antibody (ANCA)-associated small vessel vasculitis (ASVV). Apart from the renal function at diagnosis, there are no other established risk factors for renal outcome in ASVV. We have previously reported that in other forms of glomerular di...
متن کاملIs serum HMGB1 a biomarker in ANCA-associated vasculitis?
BACKGROUND Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are systemic inflammatory disorders that include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), Churg-Strauss syndrome and renal limited vasculitis (RLV). Extracellular high-mobility group box 1 (HMGB1) acts as an alarmin and has been shown to be a biomarker of disease activity as well a...
متن کاملInterstitial Lung Disease with ANCA-associated Vasculitis
The association between interstitial lung disease (ILD) and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), particularly microscopic polyangiitis (MPA), has been described in a number of case reports and case series reports in the last 2 decades. In addition, patients with pulmonary fibrosis and ANCA positivity but without other manifestations of systemic vasculitis hav...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2019
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kez057.032