021 Computer modelled coronary physiology and “virtual” fractional flow reserve from rotational angiography: Abstract 021 Figure 1

Virtual fractional flow reserve from coronary angiography: modeling the significance of coronary lesions: results from the VIRTU-1 (VIRTUal Fractional Flow Reserve From Coronary Angiography) study.

OBJECTIVES The aim of this study was to develop a computer model that accurately predicts myocardial fractional flow reserve (FFR) from angiographic images alone, in patients with coronary artery disease. BACKGROUND Percutaneous coronary intervention (PCI) guided by FFR is superior to standard assessment alone. FFR-guided PCI results in improved clinical outcomes, a reduction in the number of...

Computed Fractional Flow Reserve (FFTCT) Derived from Coronary CT Angiography

Recent advances in image-based modeling and computational fluid dynamics permit the calculation of coronary artery pressure and flow from typically acquired coronary computed tomography (CT) scans. Computed fractional flow reserve is the ratio of mean coronary artery pressure divided by mean aortic pressure under conditions of simulated maximal coronary hyperemia, thus providing a noninvasive e...

Visual-functional mismatch between coronary angiography and fractional flow reserve.

OBJECTIVES The goal of this study was to identify clinical and lesion-specific local factors affecting visual-functional mismatch. BACKGROUND Although lesion severity determined by coronary angiography has not been well correlated with physiological significance, the mechanism of the discordance remains poorly understood. METHODS The authors assessed quantitative coronary angiography, intra...

Fractional Flow Reserve and Coronary Computed Tomographic Angiography

Background: Invasive Fractional Flow Reserve Obstructive coronary artery disease (CAD) produces symptoms and increases the risk of adverse cardiac outcomes. However, determining whether a particular coronary stenosis is responsible for causing myocardial ischemia can be challenging, even with invasive coronary angiography (ICA). To help guide decisions in the cardiac catheterization laboratory,...

Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve