008 * RNASE1 AS A POTENTIAL MEDIATOR OF REMOTE ISCHAEMIC PRECONDITIONING FOR CARDIOPROTECTION
نویسندگان
چکیده
منابع مشابه
Cardioprotection by remote ischaemic preconditioning.
Perioperative myocardial infarction is a leading cause of morbidity and mortality after major non-cardiac surgery. Pharmacological agents such as beta-blockers may reduce the risk but are associated with side-effects and may be contra-indicated in some patients. Basic scientific experiments and preliminary clinical trials in humans suggest that remote ischaemic preconditioning (RIPC), where bri...
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AIMS It has been suggested that mitochondrial reactive oxygen species (ROS), Akt and Erk1/2 and more recently the mitochondrial permeability transition pore (mPTP) may act as mediators of ischaemic preconditioning (IPC), although the actual interplay between these mediators is unclear. The aim of the present study is to determine whether the cyclophilin-D (CYPD) component of the mPTP is require...
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متن کاملTime for reassessment of remote ischaemic preconditioning.
Ischaemia–reperfusion (IR) injury is a recognized cause of perioperative morbidity and mortality affecting a wide range of surgical procedures, but particularly cardiovascular surgery. Over the past 30 years a large body of published animal and clinical research has suggested that ischaemic preconditioning (IPC), consisting of a limited ischaemic insult applied before the expected major ischaem...
متن کاملInvestigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection
Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was induced by giving 4 short cycles of ischemia and reperfusion, each consisting of five min. The Langendorff’s apparatus was used to perfuse the isolated rat hearts by subjecti...
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ژورنال
عنوان ژورنال: Interactive CardioVascular and Thoracic Surgery
سال: 2014
ISSN: 1569-9293,1569-9285
DOI: 10.1093/icvts/ivu276.8