α-Mangostin dari Buah Manggis, Kandidat Obat Antikanker Baru
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چکیده
منابع مشابه
Antioxidant properties of flavonoids
Flavonoids, metabolit sekunder terbanyak yang bersumber dari tanaman, telah lama dimanfaatkan sebagai obat tradisional dan secara ilmiah juga telah terbukti memiliki efek farmakologi. Senyawa ini juga memiliki beragam manfaat terhadap kesehatan sehingga sangat berpotensi sebagai bahan baku untuk pengembangan obat baru. Penelitian terbaru memaparkan pemanfaatan flavonoids sebagai antioksidan unt...
متن کاملAnticarcinogenic Effects of α-Mangostin: A Review.
Cancer chemoprevention is a promising strategy taken to block, reverse, or retard carcinogenesis. α-Mangostin, a natural xanthone isolated from the pericarps of mangosteen, represents one of the most studied chemopreventive agents. This compound has been reported to interfere with all the major stages of carcinogenesis: initiation, promotion, and progression. A number of mechanisms have been pr...
متن کاملα-Mangostin Extraction from the Native Mangosteen (Garcinia mangostana L.) and the Binding Mechanisms of α-Mangostin to HSA or TRF
In order to obtain the biological active compound, α-mangostin, from the traditional native mangosteen (Garcinia mangostana L.), an extraction method for industrial application was explored. A high yield of α-mangostin (5.2%) was obtained by extraction from dried mangosteen pericarps with subsequent purification on macroporous resin HPD-400. The chemical structure of α-mangostin was verified ma...
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Analysis of the social-cognitive substrate of scientific activity reveals that much of science functions in an inauthentic mode whereby a materialist world view constrains the authentic practice of science. But materialism cannot explain matter, as evidenced by empirical data concerning the nature of physical manifestation. Nor, then, should materialism be the basis for our interpretation of co...
متن کاملα-Mangostin Disrupts the Development of Streptococcus mutans Biofilms and Facilitates Its Mechanical Removal
α-Mangostin (αMG) has been reported to be an effective antimicrobial agent against planktonic cells of Streptococcus mutans, a biofilm-forming and acid-producing cariogenic organism. However, its anti-biofilm activity remains to be determined. We examined whether αMG, a xanthone purified from Garcinia mangostana L grown in Vietnam, disrupts the development, acidogenicity, and/or the mechanical ...
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ژورنال
عنوان ژورنال: Farmasetika.com (Online)
سال: 2019
ISSN: 2528-0031
DOI: 10.24198/farmasetika.v4i2.22533