β-carotene Rescues Busulfan Disrupted Spermatogenesis Through Elevation in Testicular Antioxidant Capability
نویسندگان
چکیده
منابع مشابه
Effects of caudal elevation on testicular function in rats. Separation of effects on spermatogenesis and steroidogenesis.
A variety of biologic processes are perturbed when exposed to microgravity (space flight) for more than 7 days, including testicular function. Suspension of rats in a special harness (caudal elevation) to induce thoracic pooling of blood fluids and remove the support function of the hind limbs is used to mimic, on earth, the effects of microgravity encountered during space flight. Typically, th...
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BACKGROUND Some adult stem cells persist in adult tissue; however, we do not know how to stimulate stem cells in adults to heal injuries. Liver growth factor (LGF) is a biliprotein with hepatic mitogen activity. Its concentration increases markedly in the presence of any type of liver injury, and it shows in vivo therapeutic biological activity at extrahepatic sites. METHODS We have analyzed ...
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Estrogens play important roles in the regulation of testis development and spermatogenesis. Moreover, several evidences suggest that estrogen signaling can be involved in testicular tumorigenesis. The physiological effects of estrogen are mediated by the classical nuclear estrogen receptors ESR1 and 2, which regulate both genomic and rapid signaling events. In the recent years, a member of the ...
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Development of vitamin A-rich cereals can help in alleviating the widespread problem of vitamin A deficiency. We report here significant enhancement of kernel β-carotene in elite maize genotypes through accelerated marker-assisted backcross breeding. A favourable allele (543 bp) of the β-carotene hydroxylase (crtRB1) gene was introgressed in the seven elite inbred parents, which were low (1.4 µ...
متن کاملIs ß-carotene an antioxidant?
ß -carotene is a human nutrient found in plants or animals. It is also can be synthesized chemically. It is lipid-soluble, and is yellow, orange or red in color. ß-Carotene can be cleaved into vitamin A in vivo. The most abundant form of ß-carotene in human serum is trans isomer; cis isomers such as 9-cis ß-carotene, 13-cis ß-carotene, and 15-cis ß-carotene are only present in trace amounts. ß-...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: 1663-9812
DOI: 10.3389/fphar.2021.593953