β-Arrestin1–Biased β 1 -Adrenergic Receptor Signaling Regulates MicroRNA Processing
نویسندگان
چکیده
منابع مشابه
β-arrestin1-biased β1-adrenergic receptor signaling regulates microRNA processing.
RATIONALE MicroRNAs (miRs) are small, noncoding RNAs that function to post-transcriptionally regulate gene expression. First transcribed as long primary miR transcripts (pri-miRs), they are enzymatically processed in the nucleus by Drosha into hairpin intermediate miRs (pre-miRs) and further processed in the cytoplasm by Dicer into mature miRs where they regulate cellular processes after activa...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2014
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.114.302766