منابع مشابه
-Amyloid Monomers Are Neuroprotective
Maria Laura Giuffrida,1 Filippo Caraci,1 Bruno Pignataro,2 Sebastiano Cataldo,2 Paolo De Bona,3 Valeria Bruno,4,5 Gemma Molinaro,5 Giuseppe Pappalardo,6 Angela Messina,7 Angelo Palmigiano,7 Domenico Garozzo,7 Ferdinando Nicoletti,4,5 Enrico Rizzarelli,3,8 and Agata Copani1,6 1Department of Pharmaceutical Sciences, University of Catania, Catania 95125, Italy, 2Department of Physical-Chemistry, U...
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The oligomer of β-amyloid (Aβ) is considered the main neurotoxin in Alzheimer's disease (AD). Therefore, the inhibition of the formation of Aβ oligomer could be a target for AD therapy. In this study, with the help of the dot blotting assay and transmission electronic microscopy, it was have discovered that 5-hydroxycyclopenicillone, a cyclopentenone recently isolated from a sponge-associated f...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2009
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1736-09.2009