dendrimer synthesis strategies now provide virtual control of macromolecular nanostructures as a function of size and surface/interior functionality. these strategies involve the covalent assembly of hierarchical components reactive monomers , branch cells or dendron’s around atomic or molecular cores according to divergent/convergent dendrite branching principles.combinon of two or more dendrimers led us to new macromolecule which called as megamers.megamers is constricted by two specific parts so called as core and shell. core and shell could be the same or different dendrimer. in this study gn and gm of pamam dendrimers with various generation and - nh2 and - cooh end groups have been synthesized and formed as megamers. the megamer have been characterized by 1hnmr, 13cnmr, gpc, atr-ftir analytical instrument.