Over 30 years of clinical use of emergency contraception has confirmed that such methods substantially reduce the chances of pregnancy, do not entail onerous service provision requirements, and are acceptable to women. The major obstacle to the more widespread use of postcoital methods is a lack of awareness on the part of both potential acceptors and service providers of this important option...

Emergency contraception decreases the risk of unintended pregnancy after unprotected sexual intercourse or after suspected failure of routine contraception (e.g., a condom breaking). Oral methods include combined contraceptive pills (i.e., Yuzpe method), single- or split-dose levonorgestrel, and ulipristal. The Yuzpe method and levonorgestrel are U.S. Food and Drug Administration-approved for u...

Knowledge and use of emergency contraception world-wide is extremely limited. Recent research has demonstrated that levonorgestrel alone is at least as effective as the Yuzpe regimen and is much better tolerated. Levonorgestrel is likely to become the method of choice in the early 21st century. Mifepristone is highly effective even at doses which are not abortifacient. Efficacy cannot be calcul...

-the; A major reduction in the number of unwanted pregnancies and pregnancy terminations could be achieved if an effective method of emergency pregnancy interception (postcoital contraception) was readily available to women. This policy stakmnt describes a method which is the Yuzpe 2 + 2 regimen; the use of two tablets of estradioI/levonorgestrel, with an antiemetic, followed by a second identi...

The purpose of this study was to provide revised estimates of the effectiveness of the Yuzpe method of emergency contraception. Through a literature search, we identified eight studies that present the number of women treated and outcome of treatment by cycle day of unprotected intercourse relative to expected day of ovulation. Using five sets of external estimates of conception probabilities b...

The ideal emergency contraceptive would be highly effective (surpassing the 75% effectiveness rate of the Yuzpe method), free of side effects, non-disruptive of the menstrual cycle, easily administered, interceptive, and affordable. Prevention of fertilization rather than ovulation would be an important advance since it would increase the window of time after unprotected intercourse that a dru...

vidual from conception through embryonic and fetal period to birth,” where conception is defined as “the beginning of pregnancy, usually taken to be the instant that a spermatozoon enters an ovum and forms a viable zygote.”5 In a previous review6 of the mechanism of action of OCs, we concluded that they act at times via a postfertilization effect, that is, after fertilization and prior to the c...

new method has arrived, we know more about how to optimise treatment, and new distribution channels are opening up. Combined with the political will, these advances should significantly reduce the burden of unwanted pregnancies. One of the important new ingredients is the WHO trial demonstrating the superior efficacy of levonorgestrel used on its own; the pregnancy rate with levonorgestrel alon...

new method has arrived, we know more about how to optimise treatment, and new distribution channels are opening up. Combined with the political will, these advances should significantly reduce the burden of unwanted pregnancies. One of the important new ingredients is the WHO trial demonstrating the superior efficacy of levonorgestrel used on its own; the pregnancy rate with levonorgestrel alon...

we aimed to compare acceptability of levonorgestrel with the yuzpe regimen among iranian women based on their side-effects and resulting changes in the amount and pattern of menses.five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into ln...