The study is aimed at investigating the occurrence of writers cramp in office workers, drawn from ten major offices of Kanpur to determine the nature and relationship of various emotional factors in the development of this disability. The observations on writers cramp cases were compared with a group of normal and diseased controls. Out of a surveyed population of 3,325 office workers, there we...

Previous research has demonstrated a relationship between the regularity of motor production and the ability to make accurate perceptual judgments. The current study investigated the temporal abilities of two groups of patients with known movement problems (musicians' and writers' cramp), some of whom have had many years of training in temporal discrimination. Patients and controls (musician an...

Although cramp has been mentioned as a symptom by several writers on the subject of prolapsed intervertebral discs (Bradford and Spurling, 1941; O'Connell, 1943; Lenhard, 1947) no study has hitherto been made of its exact nature, frequency, and relationships. It was not until the routine follow-up of cases of sciatica, which had been treated surgically, was begun that it was noticed that the sy...

CONTEXT Electrically induced muscle cramps (EIMC) do not last long enough to study many cramp treatments. Increasing stimulation frequency lengthens cramp duration; it is unknown which frequency elicits the longest EIMC. OBJECTIVE To determine which stimulation frequency elicits the longest EIMC and whether cramp duration and stimulation frequency are correlated. DESIGN Randomized, crossove...

Mammalian antimicrobial proteins, such as defensins and cathelicidin, have stimulating effects on host leukocytes. Cathelin-related antimicrobial peptide (CRAMP), the orthologue of human cathelicidin/LL-37, is the sole identified murine cathelicidin. CRAMP has been shown to have both antimicrobial and angiogenic activities. However, whether CRAMP, like human cathelicidin/LL-37, also exhibits a ...

Muscle cramp was induced in one head of the gastrocnemius muscle (GA) in eight of thirteen subjects using maximum voluntary contraction when the muscle was in the shortened position. Cramp in GA was painful, involuntary, and localized. Induction of cramp was indicated by the presence of electromyographic (EMG) activity in one head of GA while the other head remained silent. In all cramping subj...

Neutrophils kill invading pathogens by AMPs, including cathelicidins, ROS, and NETs. The human pathogen Staphylococcus aureus exhibits enhanced resistance to neutrophil AMPs, including the murine cathelicidin CRAMP, in part, as a result of alanylation of teichoic acids by the dlt operon. In this study, we took advantage of the hypersusceptible phenotype of S. aureus DeltadltA against cationic A...

In this study, the initiation and development of muscle cramp are investigated. For this, we used a 64-channel surface electromyogram (EMG) to study the triceps surae muscle during both cramp and maximal voluntary contraction (MVC) in four cramp-prone subjects and during cramp only in another four cramp-prone subjects. The results show that cramp presents itself as a contraction of a slowly mov...