Matrix metalloproteinases (MMP) are considered to be critically involved in tumor invasion and the metastasis of various cancers. MMI-166 is a selective inhibitor of matrix metalloproteinase (MMP-2, MMP-9, and MMP-14). The purpose of this study was to evaluate the effects of MMI-166 on both the growth of the implanted tumor and the lymph node metastasis of the mediastinum and prolonging the lif...

DESCRIPTION A 36-year-old man presents to the plastic surgeon's office for consultation regarding his desire for liposuction. He is overall healthy with a nonsignificant medical history. His height and weight are 166 cm and 68.2 kg, respectively.

I . Rates of disappearance of glucose from ligated loops of small intestine in lambs, adult sheep and young rats were studied. The concentration of glucose in the lumen decreased exponentially with time, suggesting that within a range of concentrations of 166-277 m-moles/l glucose was absorbed mainly by passive diffusion. 2. The rate of absorption of glucose from a 166 mM-solution based on eith...

to determine the relation between birth weight and age of presentation of type 1 diabetes and assess its risk factors, a case-control study was done on all diabetic patients under the age of 15, who were registered in shiraz diabetic center or admitted in namazi hospital. a case group of 87 diabetic patients were matched with a control group of 100 healthy individuals. birth weight ≥ 4kg was de...

Case study: A 43-year-old man with a long history of obesity presented to our Weight Management Center 5 years after being disabled in a motor vehicle accident and gaining weight to a lifetime high of 269 kg and body mass index (BMI) of 85 kg/m. His comorbidities were hypertension, obstructive sleep apnea, gastroesophageal reflux disease, gout, and osteoarthritis, and he had recently developed ...

To determine the relation between birth weight and age of presentation of type 1 diabetes and assess its risk factors, a case-control study was done on all diabetic patients under the age of 15, who were registered in Shiraz Diabetic Center or admitted in Namazi Hospital. A case group of 87 diabetic patients were matched with a control group of 100 healthy individuals. Birth weight ≥ 4kg was de...

OBJECTIVES To assess the pharmacokinetics of moxifloxacin in morbidly obese patients. METHODS Twelve morbidly obese patients (2 male/10 female, age 25-61 years, weight 98-166 kg, body mass index 43.0-58.2 kg/m(2)) scheduled for gastric bypass surgery were treated with 400 mg of moxifloxacin orally once daily for 3 days and with 400 mg of moxifloxacin intravenously on day 4 (day of surgery). P...

The effects of a municipal solid waste compost (MSWC) (from Villarrasa-HuelvaSpain) on growth, yield and mineral composition of tomato plants (Lycopersicon esculentum Miller, cv. Genaro) were studied. Results were compared with those observed both without the application of organic matter (Control) and with the app1ication of a commercial compost AC (made from sheep manure). Soils of the three ...

OBJECTIVE To assess the effects of exenatide on body weight and glucose tolerance in nondiabetic obese subjects with normal or impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). RESEARCH DESIGN AND METHODS Obese subjects (n = 152; age 46 +/- 12 years, female 82%, weight 108.6 +/- 23.0 kg, BMI 39.6 +/- 7.0 kg/m(2), IGT or IFG 25%) were randomized to receive exenatide (n = 73) ...