vinca minor, vinca major, vinca variegata and vinca rosea are different species of vinca genus, of apocynaceae family. in addition to ornamental applications, they are placed in the group of medicinal plants , because of the various alkaloids they possess. the purpose of this research was the investigation of the antileishmanial effects of the methanolic and crude extracts of leaves and stems o...

the hydroalcoholic extracts of dried ligulate florets of calendula officinalis l., dried leaves of plantago major l., and dried aerial parts of vinca major l. were prepared and used as the main active ingredients of two types of anti-anorectal disease ointments and suppositories. benzocaine was used in one of the formulations, while a mixture of belladonna dry extract and ephedrine sulfate was ...

indole ahloids of vinca species are valued greatly in medical sciences, one reason being for their use as powerful anticancer agents. there are four species of vinca in iran: v. rosea, v. major, v. minor and v. herbacea. in previous investigations, we found that these plants have considerable alkaloid similarity (58.8- 75%). therefore, chromosomic and electrophuretic studies followed after inve...

vinca major, minor and rosea are three species of vinca genus and apocynaceae family. the present work is to investigate antimicrobial effects of these plants against candida albicans, pseudomonas aeroginosa and staphylococus aureus. alkaloids from leaf extracts had a better effect on pseudomonas aeroginosa than alkoloids from stem and root. alkaloids from stem extracts were more effective than...

Indole ahloids of Vinca species are valued greatly in medical sciences, one reason being for their use as powerful anticancer agents. There are four species of Vinca in Iran: V. rosea, V. major, V. minor and V. herbacea. In previous investigations, we found that these plants have considerable alkaloid similarity (58.8- 75%). Therefore, chromosomic and electrophuretic studies followed after i...

Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have been used as disinfectants. The vinca alkaloids are also important for being cancer fighters. There ar...

Chemotherapy-induced peripheral neurotoxicity is a major problem because it represents the dose-limiting side effect of a significant number of antineoplastic drugs, such as vinca alkaloids. Hereditary neuropathies usually predispose to severe vincristine neurotoxicity. Here, we report the case of a 56-year-old man with Machado-Joseph disease, also known as spinocerebellar ataxia type 3, treate...

On direct comparison by TLC and IR we established that the alkaloids A-5 and A-4, first isolated from Vinca herbacea W. K . 1 are identical to the oxindole alkaloid majdine (I), later isolated from Vinca major L. 2' 3 and with its isomer isomajdine (II), prepared by heating of (I) in acetic anhydride 2. Based upon some spectroscopic evidence it was claimed2, that majdine was a diastereomer of c...