Urinary tract infections (UTIs), mostly caused by uropathogenic E. coli (UPEC), are important human infections. Understanding UTI pathogenesis is for combating the rise in treatment failure and recurrent

the ability of uropathogenic e. coli (upec) to cause symptomatic uti is associated with the expression of a variety of virulence factors. biofilm formation enables upec to resist the flow of urine and increases its tolerance to antimicrobials and the host immune response. the measurement of biofilm formation in vitro is affected by the type of culture medium used. the aim of this study was to e...

results we found a high number of pai markers such as pai icft073, pai iicft073, pai i536, pai iv536, pai ii j96 and pai ii536 significantly associated with upec. the pai iv536 was the most detected ones among fecal e. coli isolated from healthy people while pai i536, pai ii536 and pai ij96 were not seen. pcr phylogenetic groups typing revealed that uropathogenic strains were mainly found in b2...

abstract bachground and objectives: the ability of adherence to the surface of host cell is very critical in the colonization of microbial pathogens. it has been revealed that e. coli strains that infect urinary tracts have different fimbrea such as i, s, fic, dr, and fimbrial adhesions. material and methods: in this study, 363 urine samples were obtained from patients with urinary tract infect...

Escherichia coli is the major aetiological agent of urinary tract infections (UTI). Like diarrhoeagenic strains of E. coli, uropathogenic isolates possess virulence determinants that distinguish them from commensal strains and allow them to produce the clinical manifestations associated with UTI. Several autotransporter proteins have been associated with the ability of E. coli, and other Gram-n...

The ability of uropathogenic E. coli (UPEC) to cause symptomatic UTI is associated with the expression of a variety of virulence factors. Biofilm formation enables UPEC to resist the flow of urine and increases its tolerance to antimicrobials and the host immune response. The measurement of biofilm formation in vitro is affected by the type of culture medium used. The aim of this study was to e...

Although many proteins have been described involved in Escherichia coli colonization and infection, only few reports have shown lectins as important components in these processes. Because the mechanisms underlying E. coli colonization process involving lectins are not fully understood, we sought to identify the presence of other non-described lectins in E. coli. Here, we isolated a 75-kDa prote...

Copper plays a dual role as a nutrient and a toxin during bacterial infections. While uropathogenic Escherichia coli (UPEC) strains can use the copper-binding metallophore yersiniabactin (Ybt) to resist copper toxicity, Ybt also converts bioavailable copper to Cu(II)-Ybt in low-copper conditions. Although E. coli have long been considered to lack a copper import pathway, we observed Ybt-mediate...

Uropathogenic Escherichia coli (UPEC) causes serious infections in people at risk and has a significant environmental prevalence due to contamination by human and animal excreta. In developing countries, UPEC assumes importance in certain dwellings because of poor community/personal hygiene and exposure to contaminated water or soil. We report the complete genome sequence of E. coli strain NA11...

To determine the presence of some toxins of diarrheagenic Escherichia coli (DEC) in uropathogenic E. coli (UPEC), 138 urinary tract infection (UTI)-causing UPECs were analyzed. The astA , set , sen and cdtB genes were detected in 13 (9.4%), 2 (1.3%), 13 (9.4%) and 0 (0%) of UPEC isolates respectively. The results show that some genes encoding toxins can be transferred from DEC pathotypes to UPE...