background: two questions about diagnostic value of urinary neutrophil gelatin associated lipocalin (ungal) in detection of acute kidney injury (aki) in children have remained unanswered; first, which cut-off point of ungal has the highest value in detection of aki; and second when is the best time for measuring this biomarker in a patient? accordingly, the present study aimed to conduct a syst...

BACKGROUND This study was conducted to determine whether there is an association between urinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary transforming growth factor-β1 (uTGF-β1) with lupus nephritis (LN) disease activity. METHODS Urine samples from 18 LN patients were collected every month for six months then examined for uNGAL, uTGF-β1, and renal domain Systemic Lupus E...

BACKGROUND Sepsis is the most common cause of acute kidney injury (AKI). Very few studies have investigated the predictive properties of urinary neutrophil gelatinase-associated lipocalin (uNGAL) as a marker of AKI in septic patients. The aim of this study is to examine uNGAL in septic patients with and without AKI and to evaluate its predictive value. METHODS We prospectively studied 155 pat...

Background: Vesicoureteral reflux (VUR) is the most common congenital urinary tract abnormality in children. Renal parenchymal damage devastating complication of severe undiagnosed VUR. Different diagnostic biomarkers have been introduced as alternatives for radiologic evaluation these patients. This review article aimed to increase knowledge about role urine neutrophil gelatinase-associated li...

BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for the early prediction of renal damage and the progression of chronic kidney disease (CKD) in humans and dogs. HYPOTHESIS Neutrophil gelatinase-associated lipocalin also may play a role in the progression of CKD in cats. ANIMALS Eighty CKD and 18 control cats. METHODS Cats were categorized into different stages ...

Neutrophil gelatinase-associated lipocalin (NGAL) is a neutrophil-derived protein whose concentration increases in plasma and urine with ongoing renal damage. Urinary leucocytes can be a potential source of urinary NGAL. The aim of this study is to investigate the effects of urinary neutrophil count and other urinary parameters on urinary NGAL values in urine with negative culture. Urinalysis, ...

Background: Delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. Difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. We investigated whether measuring urinary interleukin 18 and neutrophi...

Aim: To evaluate urinary excretion of Neutrophil Gelatinase Associated Lipocalin (NGAL) in type 2 diabetic patients with different stages of nephropathy. Methods: It was a cross-sectional study conducted at Shaikh Zayed Hospital, Lahore from Oct 2009 – Oct 2010.Ninety five subjects both males and females were divided into two groups. 75 type 2 diabetic patients (33 males and 42 females) were in...

Background: Routine diagnostic methods of Vesicoureteral reflux (VUR) are invasive and can cause exposure to radiation and may increase risk of urinary tract infections. Therefore, introducing reliable, non invasive methods might be more interested in pediatric nephrology. The objective of this perspective case control study was to evaluate the prognostic value of urinary neutrophil-gelatinase ...