نتایج جستجو برای: urea transporter B expression

تعداد نتایج: 1715338  

Journal: :iranian journal of applied animal science 2015
e. ibrahimi khoram abadi a.m. tahmasebi m. danesh mesgaran a. a. naserian a. vakili

an experiment was carried out to evaluate how interactions between forage to concentrate ratio and dietary crude protein level may alter nitrogen efficiency and ut-b expression in growing baluchi male lambs. four baluchi male lambs [30 ± 2 kg bw] were used in a 4 × 4 latin square design with 28-d periods and a 2 × 2 factorial arrangement of dietary treatments. the treatments fed forage: concent...

Journal: :Journal of the American Society of Nephrology : JASN 2004
Janet D Klein Jeff M Sands Liman Qian Xiaodan Wang Baoxue Yang

The UT-B urea transporter is the major urea transporter in red blood cells and kidney descending vasa recta. Humans and mice that lack UT-B have a mild urine-concentrating defect. Whether deletion of UT-B altered the expression of other transporter proteins involved in urinary concentration was tested. Fluorescence-based real-time reverse transcription-PCR and Northern blot analysis showed upre...

Journal: :Sub-cellular biochemistry 2014
Baoxue Yang

UT-B represents the major urea transporter in erythrocytes, in addition to being expressed in kidney descending vasa recta, brain, spleen, ureter, bladder, and testis. Expression of urea transporter UT-B confers high urea permeability to mammalian erythrocytes. Erythrocyte membranes are also permeable to various urea analogues, suggesting common transport pathways for urea and structurally simi...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2010
D Collins D C Winter A M Hogan L Schirmer A W Baird G S Stewart

Facilitative UT-B urea transporters enable the passage of urea across cell membranes. Gastrointestinal urea transporters are thought to play a significant role in the urea nitrogen salvaging process that occurs between mammalian hosts and their gut bacteria. This study investigated the expression of UT-B urea transporters in different segments of human colon. Immunoblot analysis showed that hum...

Journal: :American journal of physiology. Renal physiology 2003
Ju-Young Jung Kirsten M Madsen Ki-Hwan Han Chul-Woo Yang Mark A Knepper Jeff M Sands Jin Kim

Urea transport in the kidney is mediated by a family of transporter proteins that include the renal urea transporter (UT-A) and the erythrocyte urea transporter (UT-B). The purpose of this study was to determine the location of the urea transporter isoforms in the mouse kidney and to examine the effects of prolonged potassium depletion on the expression and distribution of these transporters by...

Journal: :Journal of Physiology Studies 2014

Journal: :Pflügers Archiv - European Journal of Physiology 2019

Journal: :American journal of physiology. Renal physiology 2005
Hideki Inoue Shelley D Kozlowski Janet D Klein James L Bailey Jeff M Sands Serena M Bagnasco

Production, recycling, and elimination of urea are important to maintain nitrogen balance. Adaptation to varying loads of urea due to different protein intake or in renal failure may involve changes in urea transport and may possibly affect urea transporters. In this study, we examined the expression of the UT-B urea transporter in rats fed a low-protein diet (LPD), a high-protein diet (HPD), a...

2007
Ju-Young Jung H. Moo Kwon Jim Kim

Urea accumulation in the renal inner medulla plays a key role in the maintenance of maximal urinary concentrating ability. Urea transport in the kidney is mediated by transporter proteins that include renal urea transporter (UT-A) and erythrocyte urea transporter (UT-B). UT-A1 and UT-A2 are produced from the same gene. There is an active tonicity-responsive enhancer (TonE) in the promoter of UT...

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