نتایج جستجو برای: ubiquinone (coenzyme q10)

تعداد نتایج: 22639  

2007

Aim: To evaluate the efficacy of an antioxidant herbomineral formulation, Addyzoa (Charak Pharma Pvt. Ltd., Mumbai, India) in oligospermia in comparison with Ubiquinone (Coenzyme Q10). Methods: A double-blind, randomised controlled trial was conducted at Dr Vaze’s clinic, Mumbai. A total of sixty patients, 30 in each group, were studied. Cap Addyzoa was administered in a dose of two capsules tw...

Journal: :iranian journal of veterinary research 2014
z. moradi s. azizi r. hobbenaghi

a common cause of peripheral nerve injury is trauma. the positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. in this experiment, the effect of intraperitoneal administration of ubiquinone (coq10) on an acute experimentally sciatic nerve crush was studied in a rat model. forty-five male wistar rats, weighing between 160-180 g were u...

2015
Anja Knott Volker Achterberg Christoph Smuda Heiko Mielke Gabi Sperling Katja Dunckelmann Alexandra Vogelsang Andrea Krüger Helge Schwengler Mojgan Behtash Sonja Kristof Heike Diekmann Tanya Eisenberg Andreas Berroth Janosch Hildebrand Ralf Siegner Marc Winnefeld Frank Teuber Sven Fey Janne Möbius Dana Retzer Thorsten Burkhardt Juliane Lüttke Thomas Blatt

Ubiquinone (coenzyme Q10, Q10) represents an endogenously synthesized lipid-soluble antioxidant which is crucial for cellular energy production but is diminished with age and under the influence of external stress factors in human skin. Here, it is shown that topical Q10 treatment is beneficial with regard to effective Q10 replenishment, augmentation of cellular energy metabolism, and antioxida...

Journal: :International journal of ophthalmology 2013
Orhan Ates Habip Bilen Sadullah Keles H Hakan Alp Mevlüt Sait Keleş Kenan Yıldırım Osman Ondaş L Can Pınar Mustafa Civelekler Orhan Baykal

AIM To determine the relationship between proliferative diabetic retinopathy (PDRP) and plasma coenzyme Q10(CoQ10) concentration. METHODS Patients with type 2 diabetes and PDRP were determined to be the case group (n=50). The control group was consist of healthy individuals (n=50). Plasma CoQ10 and malondialdehyde (MDA) levels were measured in both groups. RESULTS Ubiquinone-10 (Coenzyme Q1...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1976
T Kishi T Watanabe K Folkers

Adriamycin inhibits the succinoxidase system and the NADH-oxidase system. Both of the intact mitocondrial enzymes and the pentane-extracted preparations are inhibited. The inhibition can be prevented by a molar ratio of coenzyme to adriamycin of 3:1 for coenzyme Q10 (ubiquinone), 5:1 for coenzyme Q7, and 5:1 for coenzyme Q4. Prevention of inhibition was observed in the decreasing order of coenz...

Journal: :Redox report : communications in free radical research 2016
Adolfo Daniel Rodríguez-Carrizalez José Alberto Castellanos-González Esaú César Martínez-Romero Guillermo Miller-Arrevillaga Fermín Paul Pacheco-Moisés Luis Miguel Román-Pintos Alejandra Guillermina Miranda-Díaz

Objective To evaluate the effect of ubiquinone (Coenzyme Q10) and combined antioxidant therapy (CAT) on oxidative stress markers in non-proliferative diabetic retinopathy (NPDR) under clinical management. Study design In a randomized, double-blind, phase IIa, placebo-controlled, clinical trial, three study groups were formed and administered medications as follows: Group 1, Coenzyme Q10; Group ...

Journal: :Regulatory toxicology and pharmacology : RTP 2006
John N Hathcock Andrew Shao

Coenzyme Q10 (CoQ10) widely occurs in organisms and tissues, and is produced and used as both a drug and dietary supplement. Increasing evidence of health benefits of orally administered CoQ10 are leading to daily consumption in larger amounts, and this increase justifies research and risk assessment to evaluate the safety. A large number of clinical trials have been conducted using a range of ...

Journal: : 2022

Coenzyme Q10 (CoQ10) is a lipid-soluble component from benzoquinones. The oxidized form of ubiquinone, and the reduced ubiquinol. As well to its endogenous synthesis, also included in diet. Dietary sources CoQ10 are meat, poultry, fish, oil, nuts. has an important role energy metabolism mitochondria. It protects phospholipids, proteins, DNA oxidative damage membrane. stated that several positiv...

2012
UNNATI PITALE SHALEEN KHETARPAL KALPAK PETER VISHNU PAL ESHA VERMA PUNEET GUPTA

Periodontal disease is an inflammatory disease process, resulting from the interaction of a bacterial attack and host inflammatory response. Arrays of molecules are considered to mediate the inflammatory response including free radicals and reactive oxygen species (ROS). Periodontal pathogens can induce ROS overproduction and thus may cause collagen and periodontal cell breakdown. When ROS are ...

Journal: :applied biotechnology reports 0
sara rigi department of anatomy, school of medicine, iran university of medical science, tehran, iran abolhassan sakhae department of anatomy, school of medicine, iran university of medical science, tehran, iran azadeh niknam asl department of tissue engineering, tehran uni-versity of medical science, tehran, iran akram alizadeh department of tissue engineering, tehran uni-versity of medical science, tehran, iran fatemeh beigi department of anatomy, school of medicine, iran university of medical science, tehran, iran mehdi mehdizadeh department of anatomy, school of medicine, iran university of medical science, tehran, iran

coenzyme q10 is a promising   agent for neuroprotection in neurodegenerative   diseases. neuroprotective effects of coenzyme q10 demonstrated in some   neurodegenerative diseases such as parkinson, alzheimer and etc. hippocampus   is home of these diseases. we assayed coenzyme q10 effects on hippocampal   injury model and our hypothesis is that coenzyme q10 has neuroprotective   effects in some...

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