onychomycosis is a nail disorder associated with aesthetic problems, discomfort, physical injury and loss of dexterity. the purpose of the present study was to isolate and identify the causative fungi of onychomycosis in 2402 patients in kermanshah province, western iran in 1994 to 2010.mycologic assessment was carried out by standard methods including either microscopic or cultural procedures....

DNA sequencing analyses have demonstrated relatively limited polymorphisms within the fungal internal transcribed spacer (ITS) regions among Trichophyton spp. We sequenced the ITS region (ITS1, 5.8S, and ITS2) for 42 dermatophytes belonging to seven species (Trichophyton rubrum, T. mentagrophytes, T. soudanense, T. tonsurans, Epidermophyton floccosum, Microsporum canis, and M. gypseum) and deve...

BACKGROUND AND OBJECTIVES Onychomycosis is a common fungal infection which has been conducted in many parts of the world. The aim of this study was to evaluate the epidemiology and to identify the aetiological factors of onychomycosis in Mazandaran province, Iran. MATERIALS AND METHODS During the period of 10 years (2003-2012) 1100 patients suspected with onychomycosis, referred to the Mycolo...

Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. They include species of Trichophyton, Microsporum and Epidermophyton. In hot and humid climates of tropical and subtropical regions, the incidence of these pathogens is higher. We present in this article, the epidemiological data regarding the prevalence of different dermatophyte species involv...

A unique lipopeptide antimycotic, termed cryptocandin, is described from Cryptosporiopsis cf. quercina, an endophytic fungus. Cryptocandin, with a molecular mass of 1079 Da, contains equimolar amounts of 3,4-dihydroxyhomotyrosine, 4-hydroxyproline, threonine, glutamine, 3-hydroxy-4-hydroxymethylproline, 4,5-dihydroxyornithine and palmitic acid. Cryptocandin is chemically related to well-known a...

Fungal keratitis represents one of the most difficult forms of microbial keratitis to diagnose and treat successfully. It is difficult to obtain correct diagnosis and topical antifungal preparations. Fungi can cause severe stromal necrosis and enter the anterior chamber by penetrating an intact Descemet membrane. The most common pathogens are filamentous fungi (Aspergillus and Fusarium spp.) an...

BACKGROUND The high frequency of cutaneous mycosis justify the need to evaluate the possible contribution of in vitro profile of susceptibility to antifungal agents. OBJECTIVE To evaluate whether there is variability in in vitro susceptibility by filamentous fungi, previously isolated from cutaneous mycosis, to fluconazole, ketoconazole, itraconazole and terbinafine. METHODS Fungi were isol...

background and objectives: cattle dermatophytosis (syn. cattle ringworm), an important skin infection, has received major consideration not only for economical losses in the animal breeding industry but also in regards to its zoonotic transmission to humans. for effective control measures, it is important to determine the disease prevalence in cattle herds. materials and methods: to determine r...

Distribution and prevalence of various species of dermatophytes are not the same in different areas of the world. The aim of the present study was epidemiologic evaluation of dermatophytic infections in our area. A retrospective epidemiologic study was carried out and all patients with dermatophyte positive smears identified at the Referral Center of Southwest Iran located in the city of Ahvaz ...

BACKGROUND Since ancient time, increased interest has been witnessed in the use of an alternative herbal medicine for managing, and the treatment of fungal diseases worldwide. This may be connected to the cost and relative toxicities of the available antifungal drugs. It has been a known tradition practiced in the northern part of Nigeria that parents and teachers use the white latex of Calotro...