introduction: previous studies indicate that exercise influences cognitive function. nevertheless, considering that exercise in animal study can be voluntary, or forced, effects of exercise (specially forced exercise) on learning and memory abides as a matter of controversy. the present study aimed to investigate the effects of treadmill exercise on ltp in the dentate gyrus of rats. methods: th...

introduction: polycystic ovary syndrome (pcos) is one of the most common endocrinological pathologies in women during their reproductive years with ovulatory dysfunction, abdominal obesity, hyperandrogenism and insulin resistance. the aim of the present research was to evaluate the total antioxidant capacity (tac), total oxidant status (tos), free testosterone, ovarian morphology and estrous cy...

the aim of this study was to investigate the effect of one session of continuous exercise on a treadmill on hsp72 and tac levels of the hippocampus of male wistar rats. for this purpose, 20 male wistar rats (weight 165±1 gr. and age 6 to 8 weeks old) were assigned randomly into four groups: one control group and three acute endurance training groups (groups 1,2 and 3 were killed 30 minutes, 4 h...

nowadays, research on exercise physiology has developed. many of studies try to discover body responses or adaptations to exercise training or physical activity. in many cases, human beings are not suitable models to study these mechanisms in vivo due to ethical and legal limitations. laboratory animals especially mice and rats are appropriate models for these researches. treadmill is an excell...

Incremental cardiopulmonary exercise testing work rate ideally increases linearly to the subject's tolerance within approximately 10 min. Widely used treadmill protocols often yield shorter exercise times in debilitated patients. We compared a recently described treadmill protocol featuring linear work rate increase, weight adjustments and a priori exercise tolerance estimates with standard cyc...

background: alzheimer’s disease was known as a progressive neurodegenerative disorder in the elderly and is characterized by dementia and severe neuronal loss in the some regions of brain such as nucleus basalis magnocellularis. it plays an important role in the brain functions such as learning and memory. loss of cholinergic neurons of nucleus basalis magnocellularis by ibotenic acid can commo...

OBJECTIVE To investigate the effect of treadmill walking exercise as a treatment method to improve gait efficiency in adults with cerebral palsy (CP) and to determine gait efficiency during overground walking after the treadmill walking exercise. METHODS Fourteen adults with CP were recruited in the experimental group of treadmill walking exercise. A control group of 7 adults with CP who atte...

Epilepsy is a common neurological disorder characterized by seizure and loss of neuronal cells by abnormal rhythmic firing of neurons in the brain. In the present study, we investigated the effect of treadmill exercise on gamma-aminobutyric acid (GABA)ergic neuronal loss in relation with neuronal activation using pilocarpine-induced epileptic rats. The rats were divided into four groups: contro...

Alzheimer disease (AD) is a most common form of dementia and eventually causes impairments of learning ability and memory function. In the present study, we investigated the effects of treadmill exercise on the symptoms of AD focusing on the microglial activation-induced apoptosis. AD was made by bilateral intracerebroventricular injection of streptozotocin. The rats in the exercise groups were...

background: the present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and gaba at dentate gyrus of streptozotocin-induced diabetic rats. methods: after 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and gaba were investigated. results: the results showed that glutamate levels were significantly decreased in dia...