Estimations of the volume of extracellular fluid in man have been made by calculating the volume of body fluid through which thiocyanate is distributed after the intravenous administration of sodium thiocyanate (1, 2, 3). In the method as proposed, a known amount of sodium thiocyanate in solution is administered intravenously and blood is drawn for the measurement of the concentration of thiocy...

We used a modification of the isolated perfused rat heart, in which coronary effluent and interstitial transudate were separately collected, to investigate the localization and production of angiotensin II (Ang II) in the heart. During combined renin (0.7 to 1.5 pmol Ang I/mL per minute) and angiotensinogen (6 to 12 pmol/mL) perfusion (4 to 8 mL/min) for 60 minutes (n=3), the steady-state level...

Aim: The aim of this study is to assess the usefulness of Adenosine deaminase levels of the pleural fluid in three different groups of patients and to confirm its usefulness in the diagnosis of tuberculous effusions. Materials and methods: 25 consecutive patients admitted with their first episode of pleural of were included in the study. The routine investigations were history, clinical examina...

Abstract Objectives We aimed to investigate the usability of pleural pyruvate kinase (PK), total antioxidant status (TAS), and oxidant (TOS) as an alternative Light’s criteria in exudate-transudate differentiation. Methods This prospective study was conducted among 84 patients (42 transudates 42 exudates) with effusion. The levels PK, TAS, TOS were measured by using ELISA kits, ROC analysis use...

abstract  background: at present, differentiation between exudative and transudative pleural  effusion is based solely on laboratory measures and is time-consuming. asimple  bedside method would be of great help to differentiate between these two types of effusions.  we present a new method for this purpose assessed in 46 patients.  methods: standard laboratory tests and our method were tested ...

Pleural effusion is a common clinical problem. In the normal state, the pleural cavity is bathed in a small volume of physiologic pleural fluid containing mainly macrophages and lymphocytes. The volume of the pleural fluid can increase dramatically with most pathologic conditions affecting the pleura. The pleural effusion will alter the respiratory mechanics, commonly resulting in dyspnea. It i...

In a four-period, cross-over study, the fluoroquinolone antibacterial drug marbofloxacin (MB) was administered to calves, alone and in combination with the nonsteroidal anti-inflammatory drug tolfenamic acid (TA). Both drugs were administered intramuscularly (IM) at doses of 2 mg/kg. A tissue cage model of inflammation, based on the actions of the mild irritant carrageenan, was used to evaluate...