نتایج جستجو برای: transforming Growth Factor Beta

تعداد نتایج: 1626309  

Journal: :current medical mycology 0
alireza izadi dept. of medical mycology, faculty of medicine golamreza asadikaram dept. of biochemistry, faculty of medicine nozar nakhaee dept. of epidemiology, faculty of medicine sanaz hadizadeh dept. of medical mycology, faculty of medicine seyyed amin ayatollahi mousavi dept. of medical mycology, faculty of medicine

background and purpose: tgf-β is a potent regulator and suppressor of the immune system and overproduction of this cytokine may contribute to immunosuppression in hiv-infected patients. increasing population of immunosuppressed patients has resulted in increasingly frequent of fungal infections, including oral candidiasis. the aim of this study was to evaluate the plasma levels of tgf-β under i...

Journal: :hepatitis monthly 0
hossein khorramdelazad molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran gholamhossein hassanshahi molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran behzad nasiri ahmadabadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran mohammad kazemi arababadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran; corresponding author: mohammad kazemi arababadi, immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran. tel.: +98-3915234003-5, fax: +98-3915225209, e-mail:

results our results revealed that the serum levels of tgf-β were significantly increased in chb patients in compare to healthy controls. conclusions according to this result, it may be concluded that high serum levels of tgf-β may be a mechanism by which immune response against hbv is suppressed. background the transforming growth factor-β (tgf-β) is an important cytokine with anti-inflammatory...

Journal: :jundishapur journal of microbiology 0
seyed hossein abdollahi molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran fateme ayoobi physiology and pharmacology research center, rafsanjan university of medical sciences, rafsanjan, ir iran hossein khorramdelazad molecular medicine research center, rafsanjan university of medical sciences, rafsanjan, ir iran behzad nasiri ahmadabadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran mohammadtaghi rezayati immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran mohammad kazemi arababadi immunology of infectious diseases research center, rafsanjan university of medical sciences, rafsanjan, ir iran

conclusions based on our study, in vivo prepared e/sa may be considered as a good candidate for animal immunization. results our results showed that the serum levels of anti-e/sa immunoglobulins significantly increased in all of the immunized groups. the differences of the serum levels of tgf-β between the groups were statistically significant at days 28 and 56 after immunization with e/sa. bac...

Journal: :reports of biochemistry and molecular biology 0
mohammad reza khakzad tel: +98 9151176352; fax: +98 51- 32250048 farhad salari immunology research center, medical school, mashhad university of medical sciences, mashhad, iran maryam javanbakht department of psychiatrics, islamic azad university, mashhad branch, mashhad, iran maryam hojati noor hedayat center of autism spectrum disorders, mashhad, iran abdolreza varasteh allergy research center, mashhad university of medical sciences, mashhad, iran mojtaba sankian immunology research center, medical school, mashhad university of medical sciences, mashhad, iran

background: transforming growth factor-β1 (tgf-β1) has been found to play a crucial role in early central nervous system development. several studies have illustrated decreased tgf-β1 levels in sera and brains of autistic children. two point mutations in the tgf-β1 signal peptide at 869t/c and 915g/c have been reported to influence tgf-β1 expression. the aim of the present study was to investig...

Journal: :hepatitis monthly 0
armin hosseini razavi gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran; department of microbiology, faculty of biological sciences, shahid beheshti university, tehran, ir iran pedram azimzadeh gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran seyed reza mohebbi gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran; corresponding authors: seyed masoud hosseini, department of microbiology, faculty of biological sciences, shahid beheshti university, tehran, ir iran. tel: +98-212990-2721, fax: +98-2122736044, e-mail:; seyed reza mohebbi, gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran. tel: +98-2122432515, fax: +98-2122432516, e-mail: seyed masoud hosseini department of microbiology, faculty of biological sciences, shahid beheshti university, tehran, ir iran; corresponding authors: seyed masoud hosseini, department of microbiology, faculty of biological sciences, shahid beheshti university, tehran, ir iran. tel: +98-212990-2721, fax: +98-2122736044, e-mail:; seyed reza mohebbi, gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran. tel: +98-2122432515, fax: +98-2122432516, e-mail: sara romani gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran mahsa khanyaghma gastroenterology and liver diseases research center, shahid beheshti university of medical sciences, tehran, ir iran

objectives in this study, the association of tgf-β1 +915g/c and -509c/t gene polymorphisms with chronic hepatitis b was evaluated in iranian patients. materials and methods a population-based case–control study was conducted in taleghani hospital, tehran. a number of 220 patients with chronic hepatitis b and the same number of healthy control subjects were designated the case and the control gr...

Journal: :iranian biomedical journal 0
جلیل توکل افشاری jalil tavakkol afshari trine n jorgensen ian v hutchinson ian v hutchinson trine n jorgensen richard a kay

transforming growth factor beta (tgf-b) is a mediator released by nearly all cell types. it has suppression activity on the immune system, but exactly how this effect is carried out is not clear. previous experiments showed that igg interacts with or carriers active tgf-b, that could suppresses cytotoxic t-cell responses to an immunogenic tumor in mice. since t cell receptor (tcr) has structura...

Journal: :gene, cell and tissue 0
zahra heidari infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran; department of histology, school of medicine, zahedan university of medical sciences, zahedan, ir iran hamidreza mahmoudzadeh sagheb infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran; department of histology, school of medicine, zahedan university of medical sciences, zahedan, ir iran nadia sheibak department of histology, school of medicine, zahedan university of medical sciences, zahedan, ir iran; department of histology, school of medicine, zahedan university of medical sciences, zahedan, ir iran. tel: +98-5433295794, fax: +98-5433295794

conclusions the results of the present study showed that tgf-β1 (-509) c/t is strongly associated with quantitative parameters of connective tissue constituents of interdental papilla in cp patients. results the volume density (vʋ) of epithelium, connective tissue, collagenous and non-collagenous matrix and blood vessels had statistically significant differences between the control and chronic ...

Journal: :basic and clinical neuroscience 0
pradeep kumar department of neurology, all india institute of medical sciences, new delhi, india. amit kumar department of neurology, all india institute of medical sciences, new delhi, india. mukesh kumar srivastava department of neurobiochemistry, all india institute of medical sciences, new delhi, india. shubham misra department of neurology, all india institute of medical sciences, new delhi, india. kameshwar prasad department of neurology, all india institute of medical sciences, new delhi, india. awadh kishor pandit department of neurology, all india institute of medical sciences, new delhi, india.

introduction: transforming growth factor-beta 1 (tgf-β1) is a pleiotropic cytokine with potent anti-inflammatory property, which has been considered as an essential risk factor in the inflammatory process of ischemic stroke (is), by involving in the pathophysiological progression of hypertension, atherosclerosis, and lipid metabolisms. -509c/t tgf-β1 gene polymorphism has been found to be assoc...

Journal: :anatomical sciences journal 0
sina bozorgmehr azita parvaneh tafreshi shahsanam abbasi bahman zeynali

introduction: astrocytes, the most abundant glia in the central nervous system, modulate neuronal survival and function. astrocytic functions are mediated by synthesis and secretion of wide ranges of polypeptides through mechanism (s) poorly understood. among these, tgfβs are synthesized and released by the astrocytes. in this study, the involvement of wnt signaling pathway on the synthesis of ...

Journal: :The Journal of Japan Atherosclerosis Society 1996

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