background: this toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy federal roads of nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎ methods: autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method ...

Calvacin is a potent, antitumor mucoprotein which is cumulative in effect and which causes a prolonged intoxication characterized by anorexia and extreme weight loss. It induces a wide spectrum of lesions in experimental mammals. The more promi nent include hepatic necrosis, biliary obstruction, renal tubular necrosis, fibrinoid degeneration, myofibrillar necrosis in cardiac and skeletal muscle...

Organized data management increases the reliability of statistical analysis. The basic purpose of data management is to assure the integrity and the quality of data. To assure data validity, establishing a checking system, such as data audit, would be desirable at the following points: protocol design, supervision of study schedule, definition of data, data collection, choice of tests and proce...

mitochondria are unique organelles with major role in cellular function, not only as a major site of atp production, but also by regulating energy expenditure, apoptosis signaling, and production of reactive oxygen species. they play a central role in determining the point-of-no-return for the apoptotic process. there is accumulating evidence supporting a direct link between mitochondria, oxida...