An active role of T regulatory cells (Treg) and tolerogenic dendritic cells (Tol-DC) is believed important for the induction and maintenance of transplantation tolerance. However, interactions between these cells remain unclear. We induced donor-specific tolerance in a fully MHC-mismatched murine model of cardiac transplantation by simultaneously targeting T cell and DC function using anti-CD45...

Using biomarkers as prediction tools or therapeutic targets can be a valuable strategy in transplantation. Recent studies identified biomarkers of acute rejection (AR) and operational tolerance (TOL) through the application of meta-analysis. In this study, we comparatively analyzed the signature genes in acute rejection and operational tolerance seen in human allogeneic transplantations using m...

Drought and heat stress have become the most prevailing problems for maize (Zea mays L.) crop production. Therefore, development of tolerance has an essential goal in a breeding programme. Hence, experiment was conducted at Punjab Agricultural University, Ludhiana, to identify tolerant DH lines during spring season, 2016 2017. A total 32 were evaluated under non-stress conditions. Five indices ...

objective: in order to study genetic variation and effect of drought stress on grain yield and some morphological traits in chickpea, an experiment was conducted on 64 genotypes during 2013-2014 cropping season at deputy of kermanshah sararood dry land agricultural research institute, located on the western part of iran. methods: the experimental design was a randomized lattice design with tow ...

Objective: In order to study genetic variation and effect of drought stress on grain yield and some morphological traits in chickpea, an experiment was conducted on 64 genotypes during 2013-2014 cropping season at deputy of Kermanshah Sararood Dry Land Agricultural Research Institute, located on the western part of Iran. Methods: The experimental design was a randomized lattice design with tow ...

Objective: In order to study genetic variation and effect of drought stress on grain yield and some morphological traits in chickpea, an experiment was conducted on 64 genotypes during 2013-2014 cropping season at deputy of Kermanshah Sararood Dry Land Agricultural Research Institute, located on the western part of Iran. Methods: The experimental design was a randomized lattice design with tow ...

Six clinical isolates of Staphylococcus aureus were compared for their relative susceptibilities to the killing effects of oxacillin. Three of the strains had minimum bactericidal concentrations which were >10 times the minimum bacteriostatic concentration for this antibiotic and were designated tolerant (Tol(+)). The other strains had minimum bactericidal concentrations which were comparable t...

BACKGROUND Individuals who rapidly develop hyperthermia during heat exposure (heat-intolerant) are vulnerable to heat associated illness and injury. We recently reported that heat intolerant mice exhibit complex alterations in stress proteins in response to heat exposure. In the present study, we further explored the role of genes and molecular networks associated with heat tolerance in mice. ...

Successful induction of allograft tolerance has been achieved in nonhuman primates (NHPs) and humans via induction of transient hematopoietic chimerism. Since allograft tolerance was achieved in these recipients without durable chimerism, peripheral mechanisms are postulated to play a major role. Here, we report our studies of T cell immunity in NHP recipients that achieved long-term tolerance ...

breeding and cropping cultivars with high weed competitiveness have played an important role in the non-chemical weed management. this experiment was carried out in order to study the effect of nitrogen on weed tolerance and competition indices of five wheat cultivars at the research field of agricultural faculty, university of mohaghegh ardabili, during 2010-2011 growing season. experimental f...