In this research, aerial parts of Euphorbia denticulata Lam were collected from Sanandaj city in Kurdistan province at the West of Iran. It was extracted by maceration using acetone as solvent. Isolation of compounds were carried out with repeated column chromatography using silica gel and normal preparative HPLC using YMC-Pack-Sil column and hexane: ethyl acetate as mobile phase. The structure...

In this research, aerial parts of Euphorbia denticulata Lam were collected from Sanandaj city in Kurdistan province at the West of Iran. It was extracted by maceration using acetone as solvent. Isolation of compounds were carried out with repeated column chromatography using silica gel and normal preparative HPLC using YMC-Pack-Sil column and hexane: ethyl acetate as mobile phase. The structure...

cancer is a group of diseases characterized by uncontrolled proliferation of abnormal cells. because of the severe side effects and resistance to the traditional chemotherapeutic agents, the necessity for discovery of new anticancer drugs is a crucial topic. in the present study we synthesized new derivatives of 2-(4-fluorophenyl)- n -halophenylacetamide and assessed their cytotoxicity against ...

background: the aim of this study was to investigate the effect of methanolic extract of achillea millefolium l. (mea) on the antiproliferative activity of bleomycin on human prostate cancer and normal skin cells. materials and methods: human prostate cancer cell (du-145) and human non-malignant fibroblast cell (hfff2) were treated with mea at various concentrations ( 20, 100, 500, 1000 and 200...

Background: The aim of this study was to investigate the effect of methanolic extract of Achillea millefolium L. (MEA) on the antiproliferative activity of bleomycin on human prostate cancer and normal skin cells. Materials and Methods: Human prostate cancer cell (DU-145) and human non-malignant fibroblast cell (HFFF2) were treated with MEA at various concentrations ( 20, 100, 500, 1000 and ...

background and aims: epigallocatechin-3-gallate (egcg) is a polyphenolic compound from green tea, which its anticancer effects on many types of cancers have been confirmed, but the molecular mechanism by which egcg induces apoptosis remains unknown. the aim of the present study was to investigate anti-proliferative properties and apoptotic signaling pathway of egcg on pc3 human prostate cancer ...

One of the main components Pomegranate Seed Oil is punicic acid, an omega-5 fatty acid that capable inhibiting breast and prostate cancer cell proliferation, although mechanisms action are not yet known. In order to further understand its potential anti-cancer properties, we investigated effect on proliferation cytotoxicity human MCF-7 cells.

The synthesis by transmetallation and in-depth characterisation IR spectroscopy of five half-sandwich ruthenium osmium dithiocarbamato isonipecotamide glycoconjugate complexes are presented herein. evaluation their in vitro cytotoxicity the zinc precursors’ towards ovarian cancer (A2780 A2780cisR) normal prostate (PNT2) cells is reported. While compounds rather limited, some selectivity observed.