as drug delivery systems nanoparticulan widely investigated because of many advantages such as smaller size,controlled drug release potential targeting ability, enhancement of therapeutic efficacy and reduction oftoxicity. so, carbon nanotubes have recently received considerable attention as alternative drug delivery carrierin this study we investigate interaction of tamoxifen with open-end of ...

single-walled carbon nanotubes (swnts) are among the promising nano-devices for delivery of therapeutic agents. yet the drastic hydrophobic natures of swnts make their handling and hence application difficult.several researches have been conducted to make them more hydrophilic and water dispersible and less toxic. among the different approaches, dispersion methods exploit different reagents suc...

BACKGROUND Single-walled carbon nanotubes (SWNT) are poorly soluble in water, so their applications are limited. Therefore, aqueous solutions of SWNT, designed by noncovalent functionalization and without toxicity, are required for biomedical applications. METHODS In this study, we conjugated docetaxel with SWNT via π-π accumulation and used a surfactant to functionalize SWNT noncovalently. T...

Poly(aminobenzene sulfonic acid) (PABS) and polyethylene glycol (PEG) were covalently attached to single-walled carbon nanotubes (SWNTs) to form water-soluble graft copolymers. Quantitative near-IR (NIR) spectroscopic studies of these SWNT graft copolymers indicate a water solubility of about 5 mg/mL, and atomic force microscopy studies show a fairly uniform length and diameter. On the basis of...

Polycyclic aromatic hydrocarbons (such as, anthracene, benzo[a]pyrene and so on) are non-polar, hydrophobic compounds, which are not ionized. They are only slightly soluble in water. They are very dangerous compounds in the environment. The single-walled carbon nanotube (SWNT) is used for removal and conversion of anthracene to low-risk products. In this study, electron transfer between anthrac...

Many potential applications of single-walled carbon nanotubes (SWNTs) require that they be isolated from one another. This may be accomplished through covalent or noncovalent SWNT functionalization. The noncovalent approach preserves the intrinsic electrical, optical, and mechanical properties of SWNTs and can be achieved by dispersing SWNTs in aqueous solution using surfactants, polymers, or b...

By using molecular dynamics simulation, we have investigated systematically the feasibility of continuous unidirectional water flux across a deformed single-walled carbon nanotube (SWNT) driven by an oscillating charge outside without osmotic pressure or hydrostatic drop. Simulation results indicate that the flux is dependent sensitively on the oscillating frequency of the charge, the distance ...

polycyclic aromatic hydrocarbons (such as, anthracene, benzo[a]pyrene and so on) are non-polar, hydrophobic compounds, which are not ionized. they are only slightly soluble in water. they are very dangerous compounds in the environment. the single-walled carbon nanotube (swnt) is used for removal and conversion of anthracene to low-risk products. in this study, electron transfer between anthrac...

The cytotoxic response of cells in culture is dependant on the degree of functionalization of the single-walled carbon nanotube (SWNT). After characterizing a set of water-dispersible SWNTs, we performed in vitro cytotoxicity screens on cultured human dermal fibroblasts (HDF). The SWNT samples used in this exposure include SWNT-phenyl-SO(3)H and SWNT-phenyl-SO(3)Na (six samples with carbon/-phe...

In this work, by means of molecular dynamics simulations, we consider the mass transport of a water cluster inside a single-walled carbon nanotube (SWNT) with a diameter of about 1.4 nm. The influence of the non-equilibrium thermal environment on the confined water cluster has been investigated by imposing a longitudinal temperature gradient on the SWNT. It is demonstrated that the water cluste...